Ketoconazole - Possibly A Side Effect Free And Effective In Large Doses

[sonictemples]

Hello everyone, as you all may know ketoconazole is extremely toxic to the liver when taken orally.

However I read a study saying topical application didn't go systemic as they couldn't find traces of the drug systemically. I couldn't find the study but I remember they applied such a large dose like 40 grams to young patients

And, knowing that ketoconazole orally can be used to prevent spontaneous erections makes me think that it can be more antiandrogenic than finasteride.

Now, what if we can get this antiandrogenic benefit with large doses topically, again without systemic effects

Just my thoughts

 

[sonictemples]

The title was meant to be "a side effect drug that is effective in.." but yeah I can't change it sorri

 

[pegasus2]

It's highly potent. I haven't seen that experiment before. Maybe most of that 40g wasn't absorbed due to the high molecular weight.

 

[sonictemples]

It's highly potent. I haven't seen that experiment before. Maybe most of that 40g wasn't absorbed due to the high molecular weight.

https://pubmed.ncbi.nlm.nih.gov/3280211/
I couldn't find the study but this is the closest I can find