- Reaction score
- 320
https://www.sciencedirect.com/science/article/pii/0022473184902644
"Serenoa repens” lipidic extract (S.R.E.) was recently reported (Br. J. Pharmacoi., in press) to inhibit androgen action in animals.
S.R.E. is a good competitor for the whole cell androgen receptor
The present studies show that S.R.E. inhibits 5α-reductase, 3-ketosteroid reductase and receptor binding of androgens in cultured human foreskin fibroblasts.
As the search for the ideal antiandrogen continues, S.R.E. appears to be a new type of antiandrogenic compound as therapeutics for the treatment of benign prostatic hypertrophy, hirsutism and so forth.
"Serenoa repens” lipidic extract (S.R.E.) was recently reported (Br. J. Pharmacoi., in press) to inhibit androgen action in animals.
S.R.E. is a good competitor for the whole cell androgen receptor
The present studies show that S.R.E. inhibits 5α-reductase, 3-ketosteroid reductase and receptor binding of androgens in cultured human foreskin fibroblasts.
As the search for the ideal antiandrogen continues, S.R.E. appears to be a new type of antiandrogenic compound as therapeutics for the treatment of benign prostatic hypertrophy, hirsutism and so forth.