Hyperandrogenicity - An anabolic steroid experts view

[Empire]

I came across this page http://www.mesomorphosis.com/articles/llewellyn/proviron-and-shbg.htm

The expert made the following statement:

Lastly, you asked about avoiding the 5-alpha reductase inhibitor Propecia. Indeed, this drug does increase the androgenicity of nandrolone, making it more prone to stimulate hair loss. When taken with testosterone, however, it will reduce its relative androgenicity. So its effect here depends on the context.

Makes alot of sense to me.. Thoughts? Bryan..

 

[Axl_Rose]

I'm not smart enough to understand all that, what does it mean exactly, in layman's terms?

 

[Empire]

I'm not smart enough to understand all that, what does it mean exactly, in layman's terms?

Means Propecia makes the hair more prone to hair loss because it makes it more sensitive.

 

[Axl_Rose]

I'm not smart enough to understand all that, what does it mean exactly, in layman's terms?

Means Propecia makes the hair more prone to hair loss because it makes it more sensitive.

Oh..well isn't that f*****g fantastic....So what? We just stop taking it?

 

[Empire]

[quote="Axl_Rose":25hhgump]I'm not smart enough to understand all that, what does it mean exactly, in layman's terms?

Means Propecia makes the hair more prone to hair loss because it makes it more sensitive.

Oh..well isn't that f****ing fantastic....So what? We just stop taking it?[/quote:25hhgump]

Doesnt relate to everyone.. As you can see, it works wonders for many.

 

[Bryan]

I'm not smart enough to understand all that, what does it mean exactly, in layman's terms?

Means Propecia makes the hair more prone to hair loss because it makes it more sensitive.

Remember, what that guy said is SPECIFIC TO NANDROLONE!! If you're not taking nandrolone, disregard what he said.

 

[Empire]

I'm not smart enough to understand all that, what does it mean exactly, in layman's terms?

Means Propecia makes the hair more prone to hair loss because it makes it more sensitive.

Remember, what that guy said is SPECIFIC TO NANDROLONE!! If you're not taking nandrolone, disregard what he said.

Bryan I'm sure it's not just limited to nandrolone.. What else is Propecia making hyperandrogenetic?

 

[Jack]

It doesn't loke like a hyperandrogenity issue here , but a drug interaction between the finasteride and nandrolone - the hair loss is really caused by the androgenity of the nandrolone , which supposedly gets increased by fiansteride.

Summary : It doesn't matter for the normal finasteride user , and people are way to paranoid about finasteride causing hairloss.

 

[Empire]

It doesn't loke like a hyperandrogenity issue here , but a drug interaction between the finasteride and nandrolone - the hair loss is really caused by the androgenity of the nandrolone , which supposedly gets increased by fiansteride.

Summary : It doesn't matter for the normal finasteride user , and people are way to paranoid about finasteride causing hairloss.

No you've missed the point.

The possibility is.. Taking finasteride may cause an increase in androgenicity from another drug. That drug plays a role on the body.

What about other things that play a role, such as masturbation or even cholesterol... My point is.. Is finasteride ALSO increasing the androgenicity in them

 

[Bryan]

Remember, what that guy said is SPECIFIC TO NANDROLONE!! If you're not taking nandrolone, disregard what he said.

Bryan I'm sure it's not just limited to nandrolone.. What else is Propecia making hyperandrogenetic?

No, it _may_ not be limited to nandrolone, which is why I suggest you be very very cautious about using finasteride at the same time as any anabolic steroids.

Look, all this is OLD information! Several posters were talking about the effect of finasteride on nandrolone way back in the days of alt.baldspot, and they were warning people not to use the two drugs at the same time. It would be prudent not to use it along with any other artificial steroid (anobolic steroids), either, unless you really know what you're doing. It could backfire on you, and produce the opposite effect on your hair that you're expecting.

 

[Bryan]

It doesn't loke like a hyperandrogenity issue here , but a drug interaction between the finasteride and nandrolone - the hair loss is really caused by the androgenity of the nandrolone , which supposedly gets increased by fiansteride.

Well, that's not _quite_ correct! The point is that in the case of the synthetic steroid nandrolone, its chemical alteration by 5a-reductase makes it a LESS potent androgen, not a MORE potent one. So if you're worried about your hair while taking nandrolone, the last thing you want to do is inhibit 5a-reductase with finasteride or dutasteride. In fact, finasteride and dutasteride will have the OPPOSITE effect on nandrolone: they'll make the stuff even more androgenic (indirectly) than it normally is.

 

[Empire]

Bryan.. Steroid use may be one factor.. Whatabout other factors such as masturbation, high cholesterol and so forth.

Without Propecia, these things may not have any effect, but with Propecia it may increase the androgenicity

 

[Bryan]

Bryan.. Steroid use may be one factor.. Whatabout other factors such as masturbation, high cholesterol and so forth.

Without Propecia, these things may not have any effect, but with Propecia it may increase the androgenicity

Nah. Don't worry about those natural things, just the synthetic steroids like nandrolone that have the chemical structures to be affected in the way previously described.

 

[Empire]

Bryan.. Steroid use may be one factor.. Whatabout other factors such as masturbation, high cholesterol and so forth.

Without Propecia, these things may not have any effect, but with Propecia it may increase the androgenicity

Nah. Don't worry about those natural things, just the synthetic steroids like nandrolone that have the chemical structures to be affected in the way previously described.

Well I do recall someone saying when they heavily masturbated whilst on Propecia.. they broke out in more acne for a day or two.

I have a gut feeling something is linked here..

 

[pproctor]

So if you're worried about your hair while taking nandrolone, the last thing you want to do is inhibit 5a-reductase with finasteride or dutasteride. In fact, finasteride and dutasteride will have the OPPOSITE effect on nandrolone: they'll make the stuff even more androgenic (indirectly) than it normally is.

Exactly. I again note that 5-AR inhibitors cause an increase in tissue androgen sensitivity. Arguably, this is mostly mediated by an increase in the number of androgen receptors, though there are likely additional factors. In turn, this makes the hair follicle more sensitive to androgens.

Peter H. Proctor, PhD,MD