Home Made RU58841 ?!

Sir_LagaLot

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of all the darned home made topicals..i just google'd that and found a website where some guy had gotten his 'chemist friend' to whip him up a batch of RU58841. does anybody even know the ingrediants !? its a topical anti-androgen right?..

wonder if anybody else has tried making it themselves.
 

global

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Some people obtained it and made it up for themselves. They had mixed results, possibly due to quality issues with the raw material.

The best result reported was cessation of loss, (which is actually prettty good) but there seems to be just as much success using dutasteride, although of course that is not a topical.
 

ShedMaster

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I'm dissapointed with the lack of results posted with RU and fluridil. so much promise.. oh well.
 

Bryan

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Sir_LagaLot said:
of all the darned home made topicals..i just google'd that and found a website where some guy had gotten his 'chemist friend' to whip him up a batch of RU58841. does anybody even know the ingrediants !? its a topical anti-androgen right?..

wonder if anybody else has tried making it themselves.

RU58841 is indeed an antiandrogen (or androgen receptor blocker). However, its synthesis is far beyond what could be achieved by us "kitchen-sink chemists". To see what's involved in making that stuff, here's a scan of the page that describes the procedure, right out of Battmann's original 1994 paper:

http://www.geocities.com/bryan50001/RU_recipe.htm

Does THAT look like something you'd be willing to attempt on your kitchen counter?? :wink: (BTW, notice that one of the starting ingredients is actually PHOSGENE, the poison gas used during WWI! :freaked2: )

Bryan
 

silkeysmooth

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How long has RU been a "promising" treatment? It does sound awesome, but if it's been known as a potentially useful anti-androgen for over 10 years, then why has it not been marketed?
 

87david

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I also wanted to try RU58841. I found out a little info pertaining to its non-avalibility. It's an excellent article, but just scroll down till you see RU58841.

http://www.brinkzone.com/hairtoday2.html
 

ShedMaster

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87david said:
I also wanted to try RU58841. I found out a little info pertaining to its non-avalibility. It's an excellent article, but just scroll down till you see RU58841.

http://www.brinkzone.com/hairtoday2.html


wow great find on that follow up article. we have all seen his original piece but I personally had not seen this follow up article on his current conclusions for hairloss treatments. disappointing, yes. however, honest.
 

Bryan

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silkeysmooth said:
How long has RU been a "promising" treatment? It does sound awesome, but if it's been known as a potentially useful anti-androgen for over 10 years, then why has it not been marketed?

Probably for a couple of basic reasons:

1) Even the two FDA-approved treatments (Rogaine and Propecia) have been big disappointments sales-wise over the years, so nobody wants to invest the $$$ in bringing some new messy topical treatment to market.

2) RU58841 is rather expensive (and dangerous?) to produce.

Bryan
 

Old Baldy

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Bryan said:
Sir_LagaLot said:
of all the darned home made topicals..i just google'd that and found a website where some guy had gotten his 'chemist friend' to whip him up a batch of RU58841. does anybody even know the ingrediants !? its a topical anti-androgen right?..

wonder if anybody else has tried making it themselves.

RU58841 is indeed an antiandrogen (or androgen receptor blocker). However, its synthesis is far beyond what could be achieved by us "kitchen-sink chemists". To see what's involved in making that stuff, here's a scan of the page that describes the procedure, right out of Battmann's original 1994 paper:

http://www.geocities.com/bryan50001/RU_recipe.htm

Does THAT look like something you'd be willing to attempt on your kitchen counter?? :wink: (BTW, notice that one of the starting ingredients is actually PHOSGENE, the poison gas used during WWI! :freaked2: )

Bryan


Da** Bryan, I read it was hard to make but your link was written in English and I still couldn't understand 90 percent of it! :D

I guess that's one substance I won't try to make!
 
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