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How to use Nizoral to help stop hair loss

Nizoral is an anti fungal shampoo well known for treating dandruff - its role in helping people with androgenetic alopecia (male pattern baldness) has recently been touted after studies showing its efficacy in people with genetic hair loss.


How Nizoral may help to stop hair loss
Ketoconazole, the main ingredient in Nizoral, acts as a relatively mild anti-androgen. Androgen, a hormone that binds to receptors in the hair follicles can lead to the shrinking of these follicles.

Anti-androgen

Of course, when the follicles shrink the life cycle of the hair becomes shorter with every cycle, this leads to hair miniaturization. By reducing the binding of di-hydrotestosterone or DHT, Nizoral helps to reverse or slow down the process of hair loss.

Nizoral should not be seen as a hair loss treatment in it own right – rather a treatment that will enhance the effectiveness of other more potent hair loss treatments such as minoxidil and propecia. Used regularly, Nizoral could significantly boost the result of treatments like minoxidil because it creates a scalp with reduced levels of sebum.
It was found in a study by Pierard Franchimont C and his team, appearing in the journal, Dermatology, dated 1994, that ketoconazole had similar effects on hair growth to minoxidil 2%. So, Nizoral's effect on hair loss is possibly significantly underestimated.
Sebum reduction
It could also be that the positive effects of Nizoral on hair loss could stem from the fact that it is very potent at reducing the activity of the sebaceous glands thus reducing sebum production.

Because the sebaceous glands are attached to hair follicles, too much sebum would clog the hair follicles and disrupt the normal process of hair growth i.e. hair sprouting from these follicles.

Inflammation
According to the study, ketoconazole was instrumental in reducing inflammation of the scalp. It is well known that people experiencing androgenetic alopecia also experience varying degrees of inflammation of the scalp caused bys bacteria adjoining hair follicles.

Inflammation may be partly responsible for hair loss, but one thing for sure is, it does not create an environment on the scalp to promote hair growth.

How to use Nizoral
It is usually recommended for people with dandruff to use Nizoral 1 or 2 times a week at the most, but people who want to maximise its potential to help stop hair loss and aid in regrowth, should really consider using it at least 3 times a week but no more than 4 times, any more that would be unnecessary.

Cosmetic thickness of hair
Nizoral also helps to improve the cosmetic appearance of the hair. After 1 or 2 weeks of use, the hair would seem thicker. This is unlikely due to any systemic changes occurring because it is unlikely that hair could become thick so quickly.

So, this positive attribute of thickening is likely to be cosmetic. However, in the long run, some of that thickness will no doubt be as a result of some of the aforementioned positive effects.

Possible side effects
You may experience light headaches after using nizoral. This however, isn't serious and you should continue using it. If on the other hand, you continue to get headaches after each and every nizoral application, you should seek the advice of your doctor.
When you first begin treatment with Nizoral, it is possible that it may induce a shedding of hair. You should not be worried because shedding is often a precursor for many of hair loss treatments to better results, and thickening of hair.
To sum up, Nizoral might have a 3-pronged attack in fighting hair loss: sebum reduction, anti-DHT and anti-inflammation.



Hope this helps a bit!
 

decro435

Experienced Member
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23
Great summary.

Cheers.
 

rcom440

Senior Member
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122
this is a very good article. Some people would argue about "anti DHT" thing.
 
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