Genetics & Hair Loss Question

mpbsux20

Experienced Member
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^^Thats where you are wrong Hoppi.Diet changes and other things can help you only to a very minor extent[Although I would highly recommend them] and the main b**ch responsible for individuals who experience balding is upregulation of Androgens especially DHT produced by 5AR2.If you sit around reading a bunch of stuff posted on the internet,you will just keep going in circles.

If you really want to come up with new ideas,you are going to need a lab and some volunteers.With your raw energy,there is an outside chance that you can come up with something that can be useful and at the same time is natural. :)
 

armandein

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Hoppi said:
armandein said:
seaback said:
. I usually spend my days reading papers for my work, and my nights reading papers on hair loss. Enough is enough. I need to get a life !

Yeah seaback, genetics is genetics, period....
but as you are a literate in the matter, please can you cite any study regarding the genetic difference in healthy scalp hairs?
Any theory must explain the pattern of common hair loss.

What I heard is that the ones there have more androgen receptors on them.

In FACT... many things I have heard point to NUMBERS of androgen receptors being the changing factor triggering balding, and not, say, 5ar2 upregulation.

hm :)

Ones hairs with more androgen receptors on them,???? Before they suffer common hairloss? do you know any reference in healthy hairs? I don't see it
 

Hoppi

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armandein said:
Hoppi said:
What I heard is that the ones there have more androgen receptors on them.

In FACT... many things I have heard point to NUMBERS of androgen receptors being the changing factor triggering balding, and not, say, 5ar2 upregulation.

hm :)

Ones hairs with more androgen receptors on them,???? Before they suffer common hairloss? do you know any reference in healthy hairs? I don't see it

To be honest, I wish I could say more.

The evidence I have heard seems to point at an increase in androgen receptors in response to certain stimuli, possibly elevated estradiol. The reason I say this is because I have heard that the follicles in the P pattern have more ARs, and that prostate size correlates with male pattern baldness severity. This suggests that the follicles (ARs?) and the prostate are becoming sensitive at the same time(s), and probably due to the same triggers (whether pre-programmed genetics, hormonal, or otherwise).

The fact that estrogen is often associated with prostate enlargement is interesting to me, and the fact that.. I beliiieeeve less healthy men tend to have more prostate enlargement troubles (which causes the urination issues in later life?). All very interesting, but it's all speculation and my best guesses based on what I've learned already - I can't back this up much yet (but Googling any part of it should establish why I have come to sway towards this view).

Hoppi! ^^
 

armandein

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Thank you Hoppi for the answer,
I also would like know the reason of the pattern in hairloss, but, ....., it is the same with estradiol. why could affect its (supossely) increased androgen receptor only at certains hairs? Possibly there is another thing before, that make the selection of hairs to be targeted.

AR's "density" is equal in healthy scalp hairs, or don't?
 
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