For Docj077, new patents....................

[michael barry]

http://www.freepatentsonline.com/6790979.html

http://www.patentstorm.us/patents/6790979.html

http://www.freshpatents.com/Novel-curcu ... 187255.php



Curcumin psoriasis topical cream here, http://www.rejuvenation-science.com/psoria-gold.html ...............pricey as hell, ain't it?



Curcumin acne cream, http://www.naturalplaza.com/productdeta ... WEEKLY_SPL


Interesting that its used for psoriasis and acne...............

 

[docj077]

Thanks Michael.

Both acne and male pattern baldness demonstrates hyperkeratinization secondary to the action of androgens. Psoriasis, on the other hand, has been a more difficult disease to associated with androgens even though one of its microscopic findings is incredibly similar to both male pattern baldness and acne. I'll keep looking around.

 

[Armando Jose]

Acne, male pattern baldness, psoriasis,.... Are related?

A morphometric and histologic study of the scalp in psoriasis. Paradoxical sebaceous gland atrophy and decreased hair shaft diameters without alopecia.
Arch Dermatol. 1989 May;125(5):639-42.


Department of Pathology, University of Michigan Medical Center, Ann Arbor 48109-0602.
A histologic study was designed to evaluate the pilosebaceous unit of the scalp in nonpustular patch- and plaque-stage psoriasis. Punch biopsy specimens from involved and uninvolved areas of 28 patients were sectioned in a horizontal plane for qualitative and quantitative study. All samples were evaluated in a blind mode, and data were analyzed for statistical significance. There was no evidence for alopecia of any type. Sebaceous gland atrophy was a frequent concomitant in the psoriatic lesion, with probable down-sizing of the hair follicle and thinner hair shafts. Paradoxical sebaceous gland atrophy and down-sized hair follicles in psoriasis may be due to possible inhibiting effects of yet unidentified factors produced by the epidermal lesion.
PMID: 2637673 [PubMed - indexed for MEDLINE]


http://www.ncbi.nlm.nih.gov/entrez/quer ... t=Abstract


Dear docj77, do you know the work of Lorraine H Kligman?


Armando

 

[docj077]

Acne, male pattern baldness, psoriasis,.... Are related?

Only microscopically and only in one key feature....hyperkeratinization.

Dear docj77, do you know the work of Lorraine H Kligman?


Armando

No.

 

[Matgallis]

very interesting...