fluridil & propecia - any point?

[flimflam]

I haven't delved too deeply into the science behind these two, but from what I've read of fluridil it works differently to finasteride in that it "works by suppressing the hormone receptors that DHT bind to".

Would it be pointless to take this together with finasteride because finasteride actually blocks the creation of DHT?

Or would they work synergistically, giving me some extra oomph?

 

[Newbaldy84]

I use both just to be on the safe side but it's a very good question.

 

[michael barry]

synergistically.


finasteride stops about 85-90% of type two alpha five DHT from being made.

Fluridil is an androgen receptor blocker. It sits on a receptor site so that NO androgens can bind. Remember, you have other androgens like testosterone, androstenidione, Dehydroepiandorsterone, and DHEAS. Then there is the DHT that finasteride doesn't get. These other testosterone metabolites do not have near the affinity to bind with the androgen receptor as DHT does, and almost assuredly dont bind as 'solidly' with the receptor, but they can unlock the same bad downstream processes upon uptake. They dont, in other worlds, do your hair any favors.

I think fluridil could be a good addition and really help finasteride.

 

[Jacobo]

Michael, if cost were not an issue, would you use fluridil rather than spironolactone?
Thanks

 

[Sean68]

I use both just to be on the safe side but it's a very good question.

are you still liking applepoly new baldy? have just started myself are you
still getting results?

sorry for the slight hijack.

 

[flimflam]

synergistically.

hmm, interesting. thanks for the detailed explanation matey.

Might get some if I can find it.

 

[flimflam]

sorry for the slight hijack.

YOU TAKE YOUR GUNS AND YOUR BALACLAVAS ELSEWHERE OK.

OK THEN.


heh actually, I just ordered some applepoly too so I'd like to hear the results an' all...

 

[michael barry]

jacobo,

Ive had a months supply of fluridil before...............maybe a couple of years back. Im nosy and like to look at and test stuff. Its relatively an elegant little treatement. They come in vials and they give you 2mls a day of the stuff. (Id rather have a sprayer, even though I know sprayers are kinda wasteful).

spironolactone can leave a little white residue, is much better used twice a day, can smell if you are working out and the frangrance covering its own smell gets diluted, etc. Fluridil is a more elegant treatment than spironolactone, but I "kinda" dont think its as effective.

I'd love to be wrong about that. I have seen three good fluridil pictures in which someone regrew some hair. However, if it had 100% androgen-receptor blocking efficacy, it should regrow as much as one would expect RU58841 to, and those pics didn't indicate that much regrwoth.


The question about fluridil is the water degradation. Fluridil is designed to degrade in water, and thus why you wont have side effects with it. However, to get the the dermal papillas, fluridil has to pass a water layer in the scalp, and human skin itself has some moisture. So its effective enough to show some regrowth, but is it as effective as spironolactone used twice a day? Hard question, I would conservatively say that spironolactone is better. I'd like to be wrong about that though.

Then there is the cost issue. Fluridil aint cheap. WHat is it now, about 40 a month or so?

 

[JWM]

I have been off finasteride for 6 months after 8 years of use. In those 8 Years I have also used minoxidil.

For the past 6 months I've been using Fluridil and haven't lost any ground whatsoever.

I have seen three good fluridil pictures in which someone regrew some hair.

You make good points Michael, but it should be noted that the guys in those photos were pretty bald to begin with and even the BEST antiandrogen won't regrow much hair on a Norwood 5 etc.

 

[Newbaldy84]

I am behind JWM on this one. It's only antiandrogen so technically one should not expect much regrowth from this but pictures show diffrent story. I haven't seen many pictures from guys using RU and having amazing regrowth. It should stop hair loss and let thin and short hair regenerate and grow strong and healthy. That's what it does. JWM went off propecia and he should be loosing ground now that he's not on any DHT or androgen blocker but he jumped on fluridil and that shows you that fluridil works. There are many more stories like this on polish forum.
Being it aniandrogen and the pictures that were shown I think it shows amazing regrowth from whatever these guys had left on their heads.
I strongly doubt that spironolactone could be more effective. You don't hear much about people using only spironolactone and stopping their hairloss.

As to apple poly yeah I still use it. I order them every month. Do they work? It so hard to answer that I am not even going to bother. Me taking them is based on all the studies done on them and health behefit is a plus. I just wished it was a lot cheaper. 40$/month is kinda expensive for a student with a part time job.

 

[michael barry]

newbaldy,

my thought on apple poly is this......................we know the flesh of the apple still has quite a bit of proanthocyanidin oligomers in it. Apple cider vinegar almost assuredly has some proanthocyandins, pine oil has some also.........................and these are cheap. So what one could lose in quality, they could make up for in quantity. There are small amounts of quercitin in apples also. I would not be at all suprised if you could put fresh green apples in a blender and the juice made (add a little alchohol as a carrier agent or a little apple cider vinegar as a carrier agent) would have a good effect on hair


Im hopeful that some good study on fluridil will be done by some dermatology department........................but one of us could do one ourselves if we were really interested. Just test it on a patch of body hair for six months. If it works as well as it should................one should have a very thin patch of body hair or just vellus hair's where the fluridil was being applied.



JWM......................what makes the three fluridil pics exciting to me is what you pointed out. Those guys were pretty bald, and look like they are in their thirties, so to get decent regrowth like the pics indicated, there has to be some efficacy. The frontal regrowth especially on one dude.

 

[Jacobo]

..

 

[Jacobo]

Michael, thanks for your comprehensive answer. Fluridil is not cheap, but if you reply a questionary, you get 3 months for the price of 2. And I don't think I can "fit" 2ml in my scalp without running all over my forehead. I guess 1 ml will be enough for me. Also, the recent weakness of $ against Euro makes it look more expensive for US customers. That is good for me, I am buying Proxiphen. If the exchange rate were like 4 years ago, it would cost me 120 Euros, but I pay around 75. I've never been so interested in US economic forecasts...

I would like to see more studies on Fluridil, of course. In the last posts, Newbaldy and JWM make very good points. I would like to add another one I read a few weeks ago from a smart poster: If the fluridil people were just for the buck, they would make a more user friendly product. The use of alcohol, ampules, dry scalp, etc...is a bit of a pain. And they don't advertise with a lot of ingredients a la revivogen: fluridil is the only active ingredient. They could earn more money adding Saw Palmetto and Azelaic acid, etc, but it looks like they believe in their product.

 

[Beethoven]

That smart poster was JWM

http://www.hairlosstalk.com/discussions/viewtopic.php?t=35127&postdays=0&postorder=asc&start=10

 

[JWM]

 

[Jacobo]

That smart poster was JWM

Nice one