I know that looking at your father, maternal uncles, and maternal grandfather are the biggest indicators of whether or not you will go bald. My question is, is female pattern hair loss caused by the same genes? My mom actually has quite a bit of hair loss. She just turned 51 and already has the thin characteristic line down her head of female pattern hair loss. I talked to my mom about it one day and she told me not to worry, since only the females in her family have gotten it; her mother had it, and so did her mother's mother (from pictures I can see that none of their fathers went bald).
Family History and Inheritance of male pattern baldness
- Thread starter Brutus
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JZA70
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AFAIK, females need 2 copies of the balding gene (one on each of their X chromosomes) to be at risk.
Males get one X chromosome from their mother, considering both of your moms X chromosomes have the balding gene, I think you're at risk.
I'll let someone else chime in and confirm that.
Males get one X chromosome from their mother, considering both of your moms X chromosomes have the balding gene, I think you're at risk.
I'll let someone else chime in and confirm that.
JZA70
Banned
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That's not uncommon. The gene can come from either side of the family, although the maternal side has a more influential role.
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If this was true than father can never pass down male pattern baldness because he will always pass down Y chromosome and X chromosomes would hold balding gene, male pattern baldness would be totally dependant on mother's genes. If balding was attatched to the Y chromosome, than if your father has male pattern baldness than the son will have it 100%
It is surely autosomal and has nothing to do with sex chromosomes and not a simple allele diagram with 4 different genotypes
JZA70
Banned
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I didn't say that you can't inherit balding from the paternal side, I said that since his mom is balding, she has 2 copies of the balding gene and he is guaranteed to inherit one of them. The androgen receptor gene can only come from the X chromosome so an important part of balding comes from mothers side of the family because of the AR gene.
That being said, as we all know, there's multiple genes that cause balding but the maternal side has a more influential role.
This is true, but my mom's dad is still NW3 at age 90. He definitely doesn't have the gene and my grandma did (she wore a wig). Also, her (maternal grandma's) dad had prefect hair, died at 87 with a Ronald Reagan hairline. My 61 year old maternal uncle has some diffuse thinning but is still at a NW2 hairline (he has a longer hairstyle so it's hard to tell, my mom said his hair was thick when he was younger). I'm not sure how the balding gene would be on the X chromosome if both my mom and maternal grandma had it.