Dutasteride vs Finasteride

ren01

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Dustasteride 0.5mg per day in clinical trials produced far superior results compared to Finasteride at 5mg per day!

And according to the study Dutasteride has fewer side effects compared to Finasteride.

DutasterideFinasteride
0.5 mg5 mg
n = 813n = 817
Any adverse event17%20%
Any sexual event11%14%
Impotence7%8%
Decreased libido5%6%
Ejaculatory disorder1%l%
Gynaecomastial%l%

Dutasteride inhibits Type 1 AND Type 2 5ar enzymes whereas Finasteride inhibits Type 2 only.
Dutasteride supresses 90% of DHT compared to 70%.
 

JHCL1990

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Wait... WHAT?!?!?!

:dropmouth::dropmouth::dropmouth:

dutasteride has LESS side effects than finasteride? How? This can't be real. If this is serious I might think of getting on dutasteride/adding it into my daily regime.
 

g.i joey

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the whole type 1 reduction and the fact that its proven type 1 is found in the brain, is a big no no for me. I mean finasteride already gets me a little more tired than i usually am, i could only imagine what dutasteride would do.
 

ren01

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the whole type 1 reduction and the fact that its proven type 1 is found in the brain, is a big no no for me. I mean finasteride already gets me a little more tired than i usually am, i could only imagine what dutasteride would do.

Yes that's whats putting me off atm, Type 1 is found in vast amounts of the brain, inhibiting that, we don't know what the long term effects are, only study is about 5 years. If it weren't for that I'd be on dutasteride 0.5mg/day today.
 

INT

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This is a very small difference and 5 mg of finasteride is 5 times higher than the recommended dose for male pattern baldness. It makes sense to think that therefore sides are higher for people who use 5 mg compared to people who use 1 mg a day, 1 mg eod, 0,5 mg a day etc....
 

ren01

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This is a very small difference and 5 mg of finasteride is 5 times higher than the recommended dose for male pattern baldness. It makes sense to think that therefore sides are higher for people who use 5 mg compared to people who use 1 mg a day, 1 mg eod, 0,5 mg a day etc....

Thing is 1.25mg of finasteride and 5mg has the same effect in the body.
 

g.i joey

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I think you're wrong. Or else 1.25 would be prescribed for bph so obviously it's doing something more with 5mg.
 
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