Dutasteride once a week

ugh

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Due to the long half life of dutasteride, is it possible to see benefits if dutasteride was taken once a week?
 

Cornholio

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ugh said:
Due to the long half life of dutasteride, is it possible to see benefits if dutasteride was taken once a week?

Dr. Sawaya, who was involved in the Avodart trials and behind the scenes discussion as it was went thru phase II trials said in interviews that it would probably not be developed at the .5mg dose for hair loss (?higher dose?) and suggested that weekly or even monthly dosing would be considered due to the long half life." This dosing hasnt had clinical studies, of course. In followup after cessation of dutasteride, due to the long half life, DHT levels remained supressed for periods of more than 6 months (suggesting that less frequent dosing is reasonable).

"Would anyone buy a once a week, or once a month pill for an outrageous price like $20 per pill? You say that you would, but would you really?" Dr. Sawaya.
 

ugh

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So it less frequent dosing isn't unreasonable? Thankyou for your response
 

Cornholio

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ugh said:
So it less frequent dosing isn't unreasonable? Thankyou for your response

Its reasonable... but unstudied, meaning you may be the only person on the planet doing it : ) . If that doesnt scare you off you could take the week's worth (.5mg x7 = 3.5mg) once a week. That is only 1mg more than the 2.5mg DAILY dose that was studied in the phase II trials. It will be a while (weeks?) before your serum levels have stabilized.

For myself, I have an easier time remembering daily medications... and, if you miss a weekly med, you've missed a higher percentage of the dosage than if you miss a daily dose.

PS- This is not medical advice, you have no Idea who I am (for all you know Im a psychotic plumber) and this should not be construed as a consultation. We are all independant intelligent adults here, and make our own independant choices. That above is just my opinion. Best of luck (drool, giggle, giggle, drool, heh heh, sniff (scratches butt), drool.... )
 
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