dutasteride and finasteride

[hair today gone tomorrow]

How come some people are claiming to get better results on finasteride than on dutas? I mean it doesn't make any sense...but ive reason numerous sites that people have had better gains using propecia....Does dutas lower dht in ALL people who take it...or is it possible that the drug has no effect on you?

 

[stampede]

People claim all sorts of things.

And there are countless variables involved in people asessing their response to one medication versus another.

 

[hair today gone tomorrow]

People claim all sorts of things.

And there are countless variables involved in people asessing their response to one medication versus another.

Im just saying Ive gotten PMs and ive read on different boards of how people switched from finasteride to dutasteride and they claimed finasteride gave them better results...and they ultimately switched back to finasteride.

Im just wondering does anyone here have any theories as why this might be true?

 

[Pondle]

Many people are buying fakes from dodgy sites. I hope my drugs are genuine! aranoid:

 

[hair today gone tomorrow]

Many people are buying fakes from dodgy sites. I hope my drugs are genuine! aranoid:

I know one of them was on gsk dutasteride from a U.S pharmacy.

 

[Pondle]

I don't see how its possible to get worse results from dutasteride. dutasteride 0.5mg/day gives you 90% serum DHT and 55% scalp DHT inhibition. finasteride 5mg/day gives you about 70% and 38%, respectively (and there is greater variation between individuals with finasteride). The phase II results showed dutasteride to be superior to finasteride. So I just don't know how it could happen.

 

[hair today gone tomorrow]

I don't see how its possible to get worse results from dutasteride. dutasteride 0.5mg/day gives you 90% serum DHT and 55% scalp DHT inhibition. finasteride 5mg/day gives you about 70% and 38%, respectively (and there is greater variation between individuals with finasteride). The phase II results showed dutasteride to be superior to finasteride. So I just don't know how it could happen.

I dont see how either...im with you on this...thats what i posted this.

The only thing i could think of is the increase in TEST....but i really doubt thats the cause....

 

[Pondle]

I think a lot of the guys posting on these sites aren't exactly reliable or objective. Some aren't even sane. So far this week we've had a guy claiming masturbation caused him to go bald, someone else claiming that Propecia made his penis shrink, and another one publicly declaring male pattern baldness was making him suicidal. So when someone on here, apart from one of the more knowledgeable and established posters, claims something about any treatment, I take it with a pinch of salt.

 

[CCS]

I don't see how its possible to get worse results from dutasteride. dutasteride 0.5mg/day gives you 90% serum DHT and 55% scalp DHT inhibition. finasteride 5mg/day gives you about 70% and 38%, respectively (and there is greater variation between individuals with finasteride). The phase II results showed dutasteride to be superior to finasteride. So I just don't know how it could happen.

those numbers don't matter. It is the reduction inside the follicle that matters.

 

[CCS]

my brother was on finasteride for at least 2 years. Then he switched to dutas EOD with grapefruit. He has been on that for a year now. It has maintained his hair, same as the proscar. So unless his NW5 diffuse hair just stopped thinning naturally as soon as he got on proscar, and has been that way the last 3 years, I'd say the dutas is real. And the results are not noticeably better or worse.

 

[hair today gone tomorrow]

I don't see how its possible to get worse results from dutasteride. dutasteride 0.5mg/day gives you 90% serum DHT and 55% scalp DHT inhibition. finasteride 5mg/day gives you about 70% and 38%, respectively (and there is greater variation between individuals with finasteride). The phase II results showed dutasteride to be superior to finasteride. So I just don't know how it could happen.

those numbers don't matter. It is the reduction inside the follicle that matters.

is it possible the finasteride has a higher reduction in the follicle? i dont know, but i doubt it....im just going by anecdotal evidence.

I wish the fda II trials for dutas told us what percentage of guys had a positive reaction to dutasteride....we know it was 83% or so for finasteride...but we have no such number for dutasteride.

 

[CCS]

avodart reduced follicle DHT 98.5%. Proscar 5mg reduces it 90%. Propecia less than 90%. I'd guess 80.

yeah, the avodart studies were not very informative. It is also annoying that they only test the back. Why not the front, where most people have trouble?

 

[Pondle]

I don't see how its possible to get worse results from dutasteride. dutasteride 0.5mg/day gives you 90% serum DHT and 55% scalp DHT inhibition. finasteride 5mg/day gives you about 70% and 38%, respectively (and there is greater variation between individuals with finasteride). The phase II results showed dutasteride to be superior to finasteride. So I just don't know how it could happen.

those numbers don't matter. It is the reduction inside the follicle that matters.

Sure, which is about 98.5% versus 90% isn't it? But I also thought you subscribed to the theory that once almost all the type II 5AR has been taken care of, then 'leakage' from DHT produced by type I is a factor?

EDIT: sorry just started writing this before you posted the answer to my first question...

 

[CCS]

even if there is a study that shows both, you can't find it. Try to find this sentence of mine on google. Google is a piece of sh*t. It can't find it. Even use quotes on a piece of one of these sentences. It will say it can't find it.

 

[hair today gone tomorrow]

I don't see how its possible to get worse results from dutasteride. dutasteride 0.5mg/day gives you 90% serum DHT and 55% scalp DHT inhibition. finasteride 5mg/day gives you about 70% and 38%, respectively (and there is greater variation between individuals with finasteride). The phase II results showed dutasteride to be superior to finasteride. So I just don't know how it could happen.

those numbers don't matter. It is the reduction inside the follicle that matters.

Sure, which is about 98.5% versus 90% isn't it? But I also thought you subscribed to the theory that once almost all the type II 5AR has been taken care of, then 'leakage' from DHT produced by type I is a factor?

EDIT: sorry just started writing this before you posted the answer to my first question...

the numbers show that dutasteride shoudl be better.....but like i said soo many guys have said that they got better results with finasteride...and ive read that its possible finasteride could work better....i just dont see how.