castration and androgens question

abcdefg

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Do we know that if say 100 men were castrated before they lost any hair they all would never lose any hair in their lifetimes? 95 percent of every guy I have seen in real life that has there teenage hairline with absolutely no hairloss when they are 30ish has nearly no facial hair and probably no body hair. When you factor in women and lack of androgens common sense really seems to kind of collaborate with the finding that androgens are possibly if removed early enough 100 percent of the problem with male pattern baldness.
 

Bryan

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Hamilton would certainly agree with everything you said, and he certainly examined all that very closely in his time.
 

vauxall

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I must have read somewhere, I don't remember where, that after castration an adult male still produces significant quantities of testosterone for a few weeks and then it slows down, but still some testo is produced by the adrenal glands and it never gets as low as in women.
 

TEDDYRUXPIN

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It was believed that castrated eunichs in china did not suffer from male pattern baldness.

:agree:
 

GeminiX

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Well...

I don't quite know 100 people who have had an orchiectomy or chemical castration, but I do know several dozen. As far as I know, all of them have had no male pattern baldness after the the procedure, most (including myself) have actually had regrowth.

That said, in the individuals I know of, the procedure is accompanied by oestrogen HRT. This would skew the results somewhat.

If you're genuinely interested, I can make a post in a couple of TS forums and do a quick poll or two?
 

Bryan

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vauxall said:
I must have read somewhere, I don't remember where, that after castration an adult male still produces significant quantities of testosterone for a few weeks and then it slows down, but still some testo is produced by the adrenal glands and it never gets as low as in women.

I don't know about the part about testosterone still being significant for a few weeks and then slowing down, but I've read actual studies that measured testosterone in the blood before-and-after castration, and the reduction was about 90% to 95%.
 

Bryan

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GeminiX said:
If you're genuinely interested, I can make a post in a couple of TS forums and do a quick poll or two?

Yes, please do that, and post the results here.
 

abcdefg

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So if thats the case then propecia is not perfect at prevention just because testosterone isnt lowered enough, or it just doesnt inhibit enough dht? Why do castrated men not lose hair ever but some men on propecia still lose hair even if they take it early on?

So preventing all hairloss is basically completely stopping androgens?
 

treeshrew

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i'm not sure facial/body hair is related to hair loss from the head...

i've seen plenty of guys in their 30s who can't grow a beard but are totally bald.
 

abcdefg

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Thats not what I usually see. Facial hair in theory is dependant on androgens I thought. Lets just say I dont see very many girls with thick facial hair or neck beards although rarely some do. Girls dont lose there hair most of the time so I think that alone is pretty substantial evidence its linked to some degree.
 

baller234

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abcdefg said:
So if thats the case then propecia is not perfect at prevention just because testosterone isnt lowered enough, or it just doesnt inhibit enough dht? Why do castrated men not lose hair ever but some men on propecia still lose hair even if they take it early on?

So preventing all hairloss is basically completely stopping androgens?

All androgens (testosterone included) damage scalp hair follicles however type 2 DHT is by far the most damaging. Finasteride, if taken before the onset or at the very beginning of male pattern baldness can prevent male pattern baldness from progressing in most men probably.

Hair follicles become more sensitive to androgens over time. Bryan has posted studies showing psuedohermaphodites from the Dominican Republic who are naturally 5a reductase deficient from birth. They have no signs of male pattern baldness despite having normal testosterone levels.

My thoughts on this is that it takes exposure to a potent androgen (DHT) over time to make scalp hair follicles sensitive to androgens.
 
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