Can Nizoral become INEFFECTIVE overtime?

[$tackz]

Meaning, the same way bacteria can develop resistance to the same antibiotic overtime. Can the fungi it treats ever become resistant to ketoconazole with long-term usage? Any studies that show this>

Just something I've been wondering lately... alot of users on this forum report that over-time Nizoral no longer controls their dermatitis/dandruff like it used to.

 

[kalbo]

I was wondering this too actually. I used to have an oily scalp but when I started using nizoral, the problem went away. However three years later, my hair is now starting to get oily again even though I use nizoral more frequently now.

 

[Nicky]

As I know nizoral is a weak weapon in the battle against male pattern baldness
Don't expect much from it

 

[$tackz]

Which is why I asked if Nizoral becomes ineffective at controlling dermatitis, not male pattern baldness. I doubt Nizoral even has a direct action towards male pattern baldness, the hair just grows healthier from Nizoral cleaning the scalp/killing fungus.

To those who say Nizoral has anti-androgenic properties, do you think that really applies on the human head, or just in vitro?

 

[Bryan]

To those who say Nizoral has anti-androgenic properties, do you think that really applies on the human head, or just in vitro?

In the French study of Nizoral for male pattern baldness, the sebaceous glands in the scalp appeared to be reduced by about 19% or so. It seems likely that the antiandrogenic effect happens in vivo.