Dear Dr. Lee,
I have a few questions regarding the use of 1%
pyrithione zinc shampoo.
I have read several studies that show users of 1%
pyrithione zinc shampoo had a slightly higher
percentage of hairs in the anagen phase than those
using ketoconazole shampoo.
My question is, would it be beneficial to alternate
pyrithione zinc and ketoconazole? For example, using
ketoconazole 2-3 days a week and using pyrithione zinc
on the other days.
"That's a good idea. Ketoconazole and pyrithione zinc work in different ways to treat male pattern baldness, so using both shampoos should have additive benefits. Besides, the 2% ketoconazole shampoo shouldn't be used on a daily basis anyway."
Also, what is your opinion on using pyrithione zinc
while using minoxidil or Xandrox, and can the rotation
of pyrithione zinc and ketoconazole help relieve the
itching sometimes associated with finasteride use?
"Although the study showed "No advantage was seen in using both the 5% minoxidil topical solution and the 1% pyrithione zinc shampoo", there is no contraindication to the concomitant use of pyrithione zinc and minoxidil/Xandrox. It's important to note that "The benefit of the 1% pyrithione zinc shampoo used alone tended (P < 0·1) to be apparent only to the investigator."
As for 'itching associated with finasteride use', it's a rather a rare event and is associated with its side effect rather than being a direct effect of finasteride. You may have some relief of the itching from the use of a pyrithione zinc shampoo."
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I have provided some links below:
http://www.blackwell-synergy.com/links/ ... 435.x/abs/
http://www.dermatologytimes.com/dermato ... p?id=18433
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Thanks. They're very interesting and credible reports.
Richard Lee, M.D.