Hello. I been taking avodart for two weeks now and from this week, I am having sleeping problems. I am having trouble sleeping and the most I get is 30 mins to 1 hr sleep each night. Has anyone faced similar problems?
Actually, sleep issues/insomnia from Finasteride/Avodart are very likely due to 5AR I & II enzyme inhibition of these medications.
5ARIs like Finasteride and Avodart are DOCUMENTED to interfere with neurosteroid metabolism in the brain (THDOC, Allopregnanolone) and interfere with GABA-A receptor function (GABAergic system).
Additionally, 5ARIs interfere with Nitric Oxide Synthase production and release. NO (nitric oxide) is implicated in the sleep/wake cycle, low levels of which lead to a state of wakefulness.
I don't think I will go back to finasteride. I was shedding on finasteride massivelyyyyyy and I lost nearly 30% of my hairs in only 3-4 months. I have only been on avodart for 2 weeks only and my hairs kind of seem better. I will post the updates.
I *think* I noticed a regrowth surge when I switched to Avodart too, though looking back through my diary and posts here I also got them while on Finasteride.
At the time I posted something along the lines of seeing masses of fresh vellus regrowth which seemed to be considerably more than I had seen since the very first Finsateride regrowth.