Anyone Trying This? Phase 2a Study Of Setipiprant Tablets In Androgenetic Alopecia In Males

[Mach]

https://clinicaltrials.gov/ct2/show/NCT02781311

This study will evaluate the safety, tolerability and efficacy of the oral administration of setipiprant tablets 1000 mg twice daily (BID) relative to placebo and active comparator, finasteride 1 mg once daily, in 18 to 41 years old males with androgenetic alopecia (Androgenetic Alopecia).
Experimental: Setipiprant
1000 mg setipiprant (two 500 mg tablets) twice daily (BID) at 12-hour intervals for 24 weeks.
Drug: setipiprant
Two 500 mg setipiprant tablets BID.
Other Name: KYTH-105

 

[Afro_Vacancy]

Lots of people are trying black market seti (super expensive) at low doses. What I got: definitely decreses itch, topical may work better than oral for hair, might have insomnia as side effect so people take it in the morning.

 

[Mach]

Wonder why allergan is testing oral? 14 different testing locations. Is anyone looking at being a recruit?

 

[kawnshawn]

I could do the Cleveland location but they aren't recruiting right now and doesn't start until next June.

 

[abcdefg]

Don't know about you/others here, but I'd much rather take a pill than use a topical if efficacy is comparable and side effects don't differ (huge Ifs though).

Yeah that is what merk did with propecia actually and men picked oral. I know its not practical but id say release both and let men choose. Oral is more convenient but you better believe topical would be safer.

 

[buckthorn]

dang, one of these locations is right by where I live. and they are recruiting. don't think i am a candidate though

 

[farkhairloss]

Don't kitow about you/others here, but I'd much rather take a pill than use a topical if efficacy is comparable and side effects don't differ (huge Ifs though).

Yes prefer the oral route. f*** having to put sh*t in your hair everyday if you can do it orally.

 

[Mach]

dang, one of these locations is right by where I live. and they are recruiting. don't think i am a candidate though

Lie!

 

[buckthorn]

Lie!

not at all man... literally like 40min away from my home. I have been on medications for hair loss though and still am. :/

 

[Mach]

not at all man... literally like 40min away from my home. I have been on medications for hair loss though and still am. :/

I ment lie about your treatments

 

[Folliman]

We don't know if he'll be given finasteride or placebo though.

 

[farkhairloss]

Would they be able to tell if you are on anything when they take your blood tests etc when screening patients?

 

[hwezdarik]

Would they be able to tell if you are on anything when they take your blood tests etc when screening patients?

I reckon they would be looking for traces of finasteride and minoxidil in your blood. It is a multi-million dollar research and thus they can not risk having their results tainted with tested subjects being secretly on finasteride/minoxidil.

And lets face it who knows about SETI ? Only someone, who is deeply concerned about their hairloss and that someone is probably on finasteride already (as long as no sides). And that someone, would certainly like to try something new like SETI at high doses for free + being paid for it as well, withholding the fact that SETI is not the only medication taken against hairloss.

 

[Afro_Vacancy]

I wouldn't wantto be in this study:

- 33% chance of being on finasteride, no thank you;
- 33% chance of being on placebo, no thank you;
- 33% chance of being on seti, maybe;

And you're not allowed to take any other treatments.

 

[tress_dreams]

Has anyone looked into a bulk Seti order from one of the alibaba distributors? Curious how much it would cost to do maybe a 3 or 4 person group buy that would allow a 6 month supply at 1000 mg daily dosage per person.

 

[Mach]

The interesting thing is they are testing setipiprant against finasteride. I think that is bold. They must have seen something in their research.

 

[buckthorn]

The interesting thing is they are testing setipiprant against finasteride. I think that is bold. They must have seen something in their research.

yeah, that is interesting. I will be getting my seti in the mail soon. I may try 200-400mg orally per day. I will let you know if it helps with my horrendous inflammation.

 

[Afro_Vacancy]

The interesting thing is they are testing setipiprant against finasteride. I think that is bold. They must have seen something in their research.

If they're ballsy they'll compare the relative rates of low libido and erectile dysfunction in the two groups.

 

[Grasshüpfer]

Has anyone looked into a bulk Seti order from one of the alibaba distributors? Curious how much it would cost to do maybe a 3 or 4 person group buy that would allow a 6 month supply at 1000 mg daily dosage per person.

That is a really good idea. Alibaba is not necessarily crap, you have to 3rd party test it though. Im in Europe however.