Hi guys, I have an update that might interest everyone:
Blackseed extract also known as Nigella sativa, contains an active known as Tymoquinon, which exerts anti-oxidant and anti-inflammatory effects by inhibiting pro-inflammatory mediators, such as cyclooxygenase (COX) and prostaglandin D2.
Anyways, since Tymoquinon is a natural extract, it is readily available and will not undergo rigorous studies (10+ years of trials). However, in 2013 an Italian team made it up in a topical lotion and applied it to scalps suffering from Telogen effluvium and collected data over 6 months. The study is publicly available. Here's the link:
http://file.scirp.org/pdf/JCDSA_2013081513583870.pdf
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Results:
At 3 months, 90% of patients using NS solution demonstrated a significant increase in the number of hairs/cm2 in comparison to baseline (T0), while in the group of patients treated with placebo, only 30% of patients showed hair density increase.
In detail, nine out of ten patients belonging to the NS group showed an increase in hair number. Five of these patients reported a further increase at T6, while in four patients we observed a stabilization of the disease with a preservation of hair density also at follow-up. Results strongly differed from the placebo group, where six out of ten patients displayed severe hair loss at both T3 and T6, only three patients showed an improvement in hair density, and one patient showed a stabilization of the disease with the same hair density at T0 and T3
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There are photos and hair counts as well.
Anyways, the same company that makes Espumil foaming solution also manufactures Tymoquinon under the trade name Prostaquinon™, which your compounding pharmacy can prepare for you.
How to prepare if you can get your hands on it yourseld you ask?
Prostquinon™ 3 g
PEG-40 hydrogenated castor oil 12 g
Espumil™ qs 100 ml
Compounding instruction:
1.Calculate the quantity of each ingredient required for the prescription.
2.Accurately weigh or measure each ingredient.
3.Mix the Prostaquinon™ with PEG-40 hydrogenated castor oil. If required, gently heat the castor oil (using a water bath) until a liquid is formed.
4.Add approximately three quarters (75 ml) of the Espumil™ slowly to the Prostaquinon™ and PEG-40 hydrogenated castor oil solution and homogenize the solution.
5.Transfer the solution into a graduated cylinder, add qs Espumil™ to reach final volume (100 ml) and homogenize the solution.
Package in Fagron foam dispenser and label.
6.Refrigerate the final solution and it will last 3 months.
Cheers guys
- Des
