Antioxidant Developed To Reenergize And Restore Mitochondria Health

[floschen]

https://www.prnewswire.com/news-rel...ascular-health-in-older-adults-300642389.html

The interesting thing about this study is that "MitoQ" is not just an antioxidant, but one that specifically targets the mitochondria, and mitochondrial function is VERY important for hair growth. Previous studies have shown that a decrease in mitochondrial function is a big factor that contributes to aging and its symptoms like wrinkles, hair loss and less energy.

Too bad that this stuff is quite expensive

 

[ATV_87877827]

Hello

I’m glad you mentioned this subject.

There is some evidence that mitochondrial dysfunction and reactive oxygen species may have a role in androgenetic alopecia.

There’s some interesting research on “Szeto-Schiller” peptides, novel antioxidants that target the inner mitochondrial membrane. They have similarities to MitoQ. I had some papers on my old PC in which the researchers compared several antioxidants including the compounds we’ve mentioned, and they provided some interesting information. Again, we are a long way from these entering daily clinical practice, but the ideas sounded exciting, particularly Szeto-Schiller peptide 31 (SS-31). I’m sorry if this has been mentioned before, but I couldn’t seem to find much forum discussions about these antioxidant peptides.

Here’s the relevant paper:

(I think new members are not permitted to post links so I’ll just include the Pubmed ID and DOI)

PMID: 21638136

doi: 10.1007/s11095-011-0476-8

Title:

Novel therapies targeting inner mitochondrial membrane--from discovery to clinical development.

The use of these peptides and similar mitochondrial-targeted compounds has been and is currently being investigated in neurological, cardiac and renal disease since this paper was published. I wonder if they may be of any help to us (or we carry on praying for Riken/Organ technologies..)

 

[ATV_87877827]

Sorry for the double post

Did a little research on the mitochondrial-targeted therapeutic I mentioned earlier (SS-31, also known as elamipretide). This Youtube video shows some of the work thus far (Presented by Prof. Szeto, co-author of the paper mentioned in my earlier post).

Again, I’m not sure if new users are allowed to post URLs so I’ll put some spaces:

Youtube (dot) Com / watch?v=Ni8o4vuqo-M

Video title: clinical develpment of elamipretide for rare and common mitochondrial diseases

So it seems to have many potential applications e.g. heart failure, Parkinson’s disease, Alzheimer’s, ALS, diabetes, etc. Given the evidence of mitochondrial dysfunction in androgenetic alopecia, this may be worth a try. After reading about Szeto-Schiller peptides initially, I thought it sounded maybe too optimistic, but that paper gave me a little hope that these could be quite beneficial medicines.