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Alpecin or nizoral shampoo?
- Thread starter Zukias
- Start date
slurms mackenzie
Established Member
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- 6
I wouldn't rely on a shampoo alone, most people on here would go for Nizoral because Ketoconazole it's active ingredient has been proven to have a mild anti-androgen effect.
Personally Nizoral makes my head itch so i don't bother with it and instead have been using Alpecin double effect. The double effect has the added advantage of containing piroctone olamine, this study get's touted a lot.
Personally Nizoral makes my head itch so i don't bother with it and instead have been using Alpecin double effect. The double effect has the added advantage of containing piroctone olamine, this study get's touted a lot.
Synopsis: Hair shedding and hair thinning have been reported to be affected by dandruff and seborrhoeic dermatitis. The present study was conducted in 150 men presenting with telogen effluvium related to androgenic alopecia associated with dandruff. They were randomly allocated to three groups receiving each one of the three shampoos in the market containing either 1% ketoconazole (KTZ), 1% piroctone olamine (PTO) or 1% zinc pyrithione (ZPT). Shampoos had to be used 2-3 times a week for 6 months. Hair shedding during shampoo was evaluated semiquantitatively. Hair density on the vertex was evaluated on photographs using a Dermaphot. Trichograms were used for determining the anagen hair percentage and the mean proximal hair shaft diameter using computerized image analysis. The sebum excretion rate (SER, [mu]g cm-2 h-1) was also measured using a Sebumeter(R).
The three treatments cleared pruritus and dandruff rapidly. At end point, hair density was unchanged, although hair shedding was decreased (KTZ: -17.3%, PTO: -16.5%, ZPT: -10.1%) and the anagen hair percentage was increased (KTZ: 4.9%, PTO: 7.9%, ZPT: 6.8%). The effect on the mean hair shaft diameter was contrasted between the three groups of volunteers (KTZ: 5.4%, PTO: 7.7%, ZPT: -2.2%). In conclusion, telogen effluvium was controlled by KTZ, PTO and ZPT shampoos at 1% concentration. In addition, KTZ and PTO increased the mean hair shaft thickness while discretely decreasing the sebum output at the skin surface.
sir chugalot said:I wouldn't rely on a shampoo alone, most people on here would go for Nizoral because Ketoconazole it's active ingredient has been proven to have a mild anti-androgen effect.
Personally Nizoral makes my head itch so i don't bother with it and instead have been using Alpecin double effect. The double effect has the added advantage of containing piroctone olamine, this study get's touted a lot.
Do you think using both would be a good idea?
slurms mackenzie
Established Member
- Reaction score
- 6
Zukias said:sir chugalot said:I wouldn't rely on a shampoo alone, most people on here would go for Nizoral because Ketoconazole it's active ingredient has been proven to have a mild anti-androgen effect.
Personally Nizoral makes my head itch so i don't bother with it and instead have been using Alpecin double effect. The double effect has the added advantage of containing piroctone olamine, this study get's touted a lot.
Do you think using both would be a good idea?
I couldn't quantify the benefit of doing it, but if i could tolerate nizoral it's certainly something i'd consider.
I know a lot of people alternate nizoral, maybe not with alpecin but certainly other shampoos that contain piractone olamine and shampoos that contain the zinc (check out peoples regimens when they list them)