5aR deficiency

[Bismarck]

There are people having a defect of the 5 alpha reductase (they don't develop male pattern baldness) is only the type II enzyme affected or both ?


bis

 

[socks]

If you're referring to pseudohermaphrodites Bismarck I direct you to the following quote by Bryan:

He's referring to the "pseudohermaphrodites" found mainly in the Dominican Republic. Those are people with a genetic mutation that gives them a hormonal profile that's strikingly similar to that of finasteride users. They lack the 5a-R type 2 enzyme, but have perfectly normal levels of the type 1 enzyme. They never suffer from male pattern baldness, and they don't even get the "normal" post-puberty mild frontal recession that about 96% of all males experience.

Here is the link to the entire thread:

IS DHT travelling in blood irrelevant in male pattern baldness?

 

[Bismarck]

Thank you for that link !

Bryan, is there a type I deficiency as well ?