2017 Could Be The Year Crispr Finally Takes Off.

[nameless]

https://www.newscientist.com/article/2133095-boom-in-human-gene-editing-as-20-crispr-trials-gear-up/

 

[JimmyB]

Crispr is definitely a game-changer, but I have a feeling it'll be a long time before it's specifically tested on hair loss. Who knows though, maybe they'll find that editing genes to treat something else will cause people to grow more hair.

 

[nameless]

Crispr is definitely a game-changer, but I have a feeling it'll be a long time before it's specifically tested on hair loss. Who knows though, maybe they'll find that editing genes to treat something else will cause people to grow more hair.

I totally disagree.

I think that if CRISPR treatments start demonstrating safety in FDA trials (phase 1) then some scientist will give it a go to treat hair loss. A lot of people want a cure for hair loss.

CRISPR reduces costs dramatically and it also makes the process of altering genes somewhat simpler. I was reading about a guy who got FDA approval to do CRISPR editing for creating new traits in dogs in his garage.

http://gizmodo.com/the-fda-is-cracking-down-on-rogue-genetic-engineers-1791760888

Keep in mind that the person Trump appointed to run the FDA supports accelerated approval of medicines and he supports anti-aging treatments. And Trump himself takes propecia for hair loss so you know he wants a cure for his own hair loss.

 

[Kev123]

How can CRISPR stop hair loss right now though? In other words, it's gene editing, so what gene would they edit it to "switch off" male pattern baldness without any bad mutations?

 

[nameless]

How can CRISPR stop hair loss right now though? In other words, it's gene editing, so what gene would they edit it to "switch off" male pattern baldness without any bad mutations?

That's a question for someone more informed than I am.

 

[hanginginthewire]

 

[lemoncloak]

How can CRISPR stop hair loss right now though? In other words, it's gene editing, so what gene would they edit it to "switch off" male pattern baldness without any bad mutations?

Androgen receptor knockout.

I think a lot of these unexpected mutations may happen outside of the targeted gene. Crispr recognizes sequences so maybe, since the whole genome is pretty big, it hits identical sequences that happen to be in other places too. You can't control the process per se. Just set the original mechanism and throw it in there as far as i know

 

[lemoncloak]

View attachment 57128

 

[abcdefg]

How can CRISPR stop hair loss right now though? In other words, it's gene editing, so what gene would they edit it to "switch off" male pattern baldness without any bad mutations?

It wont. Trials using it for the first time are still ongoing. Will CRISPR take off this year? Yes. Will it do anything for male pattern baldness in the next few years? No.

 

[Kev123]

It wont. Trials using it for the first time are still ongoing. Will CRISPR take off this year? Yes. Will it do anything for male pattern baldness in the next few years? No.

I thought so.

On another note, in a sports website's off-topic section someone posted a thread about a hair loss cure coming and another person replied with CRISPR being the future for hair loss. It surprised me because I didn't expect anyone to really know about this other than "us". It seems like some people out there know about this and know what it can potentially do.