10 New Clinical Trials are now being conducted on Finaster..

Ende

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Like I've already expressed; that 9th study is exactly what we need.

125 mg Telogen Effluvium once a week will bring their testosterone level a bit over the normal range. Keep in mind that the participants already are hypogonadal, probably suffering from andropause; estrogen dominance. The aromatization process gets more active with supraphysiological level of testosterone, and the subjects are going to use 5 mg finasteride a day to benefit from testosterone's anabolic effect without the risk of enlarged prostate! LOL!

They're finally going to discover the ugly truth about DHT as the estrogen antagonist, and Merck should brace themselves. No more lies.
 

HT55

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Enden said:
Like I've already expressed; that 9th study is exactly what we need.

125 mg Telogen Effluvium once a week will bring their testosterone level a bit over the normal range.


Some people need more T than others so 125 mg may not bring them over the normal range or even close.

I know guys at the gym who use about 600mg/week of T and 5 mg of finasteride to prevent hair loss, what problems are you suggesting the guys in this study will run into ?
 

Ende

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HT55 said:
Enden said:
Like I've already expressed; that 9th study is exactly what we need.

125 mg Telogen Effluvium once a week will bring their testosterone level a bit over the normal range.


Some people need more T than others so 125 mg may not bring them over the normal range or even close.

I know guys at the gym who use about 600mg/week of T and 5 mg of finasteride to prevent hair loss, what problems are you suggesting the guys in this study will run into ?
Then I guess they'll give more Telogen Effluvium if needed, since all the subjects are supposed to have a supraphysiological level of testosterone during the study.

That someone is using 600mg Telogen Effluvium/C a week along with 5mg finasteride ED is impressive. I guess they have a low body fat percent? I think those probably unfit, old, hypogonadal men (andropause) are going to be suffering from heavy estrogen related side effects.
 

hairhoper

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Good news.

On the subject I finally read the sides section of my (generic prescription) Finasteride's paperwork properly and thought it was interesting what it actually said. Wasn't really what I expected. I realise this is referring to the 5mg dose, but it basically says:

Impotence is 'very common' (occurring in more than 1 in 10 patients), 'normally ... at the start of treatment', but does 'not last long in the majority of patients if the treatment continues'.

Keep taking it and you'll be fine, lols. I don't know what to think of this but I know if I was suddenly impotent a month or 2 into taking finasteride I'd stop for sure! :D

Also it says 'does not last long in the majority...'. Does this not directly imply that for some patients it does last long (is permanent)?

Then why does that seem to be a vague deduction, should that not be clearer?!!

It's also weird that testicular pain is listed as uncommon, yet I myself experienced it and I've seen loads of finasteride users in the success thread say something along the lines of 'no sides, just a bit of nut-ache', so I figured it was a common side. Somehow the list of sides and their grading seems weird to me.

I really hope these 10 studies shed some light on the situation. I'd love to see this 'Post Finasteride Syndrome' stuff explained because at the moment it's just this black cloud of fear nobody really knows whether to take seriously.

Full text from my finasteride packet below (I actually have the boxes for 2 different manufacturers and both pamphlets are worded exactly the same):
For the assessment of side-effects the following descriptions of frequency have been used.

Very common - occur in more than 1 in 10 patients
Common - occur in more than 1 in 100 patients
Uncommon - occur in less than 1 in 100 patients but more than 1 in 1000 patients
Rare - Occur in less than 1 in 1000 patients, but more than 1 in 10000 patients, including isolated reports


The most common side effects are impotence and decreased sexual drive. These effects normally occur at the start of treatment but do not usually last long in the majority of patients if treatment continues.

[...]
Very common: impotence
Common: decreased sexual drive, reduced volume of semen, ejaculation disorders, tenderness or enlargement of male breasts.
Uncommon: Testicular pain.
Very rare: secretion from the male breast(s), breast nodules.
 

sandyc

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Do you think people get nut ache from sitting at their desk for too long reading about hairloss?

Years ago, I thought I had testicular cancer and spent weeks reading about it online, then went to the Doctor and he said I was finasteride and probably sitting down for too long.
 

sandyc

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I don't take finasteride yet but being a obsessive person, I've got to the point when i know I'm BSing myself.

I've been convinced of a lot of things that were wrong with me in the past when I was actually fine. Apart from drinking I'm very healthy so curious if I'll have sides. I hope not.
 

hairhoper

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I had some pretty noticeable ball-ache on and off for about 3 days near the start of treatment. As sides go, in 6 months overall that's not all that bad, but you do wonder just what the hell was going on with your nuts and if there are any repercussions! They look and feel fine now tho, bless 'em. Good ol' nuts. :hump:

*touch-wood etc etc.*
 

fml

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sandyc said:
Do you think people get nut ache from sitting at their desk for too long reading about hairloss?

Years ago, I thought I had testicular cancer and spent weeks reading about it online, then went to the Doctor and he said I was finasteride and probably sitting down for too long.

Excellent point.

I knew for a few weeks that I was going to start finasteride before I actually started taking it. However, whist I knew, and nobody denies, there is some risk of sides while on it, I had also been driven totally insane by the propecia propeller heads on the conspiriwebs. Therefore, for those weeks before taking it, I made sure to pay close attention to physical feelings and functions in my body so that I would know if anything is different once I started finasteride. Let me just say it is amazing the aches and pains and "dysfunctions" you get that are so normal that ordinarily you dont even consciously acknowledge them. This is what I noticed:

-- Nut ache. Almost daily, particularly after having sat down at a computer for some period.

-- Itching and aches in the chest.

-- Less ejaculate. Happened when previous orgasm was recent. Also happened if intercourse/masturbation time was brief and not particularly mentally satisfying. Also happened when elasticated clothing was not removed and was restrictive under the nuts.

-- Total loss of erection, within a minute or two of penetration, on first sexual encounter with a particular woman, totally sober.

-- Total impotence on first (attempted) sexual encounter with another woman after we smoked god knows what together.

-- Noticeably reduced libido often occurred after nights of not getting enough sleep. Also occurred after days of eating too much. Also occurred after days of eating too little. Also occurred if too much of my calorie intake was from sugary sh*t or processed sh*t.

-- Noticeably lower mood. Exactly the same causes as reduced libido.

-- Noticeably less drive/energy. Exactly the same causes as reduced libido.

-- Inability to think (brain fog). Exactly the same causes as reduced libido.


Most people are completely clueless as to how massively and fundamentally rest and diet affects them physically and mentally every minute of every day.

Since my experiment I have been calmly taking finasteride for a bit over six weeks. (With nothing unusual to report so far.)
 

sandyc

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Get this, the other morning I thought to myself 'my penis seems like it's gone smaller' then realised I hadn't started taking finasteride yet but had been reading about it a lot.
 

sandyc

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Wasn't taking the piss. I'm aware people do have problems, I'm just saying how MY mind plays tricks on me and from the reading I've done here and elsewhere, for a few hours in a half asleep stuper, I thought I was getting side effects from something I hadn't even taken yet.
 

img23

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These trials are good for numerous reasons. There were still a lot of unknowns, this will help. Also might open up dutasteride, we'll see. The big thing is that this is more forward motion than we have seen in a very long time. At least it might answer a few questions, and open some doors. Good stuff.
 

ryder

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man.. i have my apointment with dr. wong in vancouver tomorrow to basically ask what i need to do and get pushed to take finasteride..

now i'm reading this, hearing about penis shrinkage etc..

god, i really hope there arn't long term serious side affects to finasteride : /
 

ryder

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finfighter said:
ryder said:
man.. i have my apointment with dr. wong in vancouver tomorrow to basically ask what i need to do and get pushed to take finasteride..

now i'm reading this, hearing about penis shrinkage etc..

god, i really hope there arn't long term serious side affects to finasteride : /

There are long term ,and persistent, side effects from Finasteride, but they only occur in some men the majority will not experience this, even the majority of those who get sides! But it does occur!

the penis size thing kinda freaks me out.

i've now found some /finasteride help forums' with sections on people complaing about size etc.

however i assuming this, if it does happen, is in a very small number of finasteride patients. correct me if im wrong, but a lot of people use finasteride right? thus i shouldn't be worried about the odd person complaing about these rediculous side effects?

sory guys, just nervous.. it;s the night before i see wong to get a perscription for finasteride so i'm all over the net right now researching.

finasteride is the only real answer (aside from min) in current science to battle hair loss, right?
 

ryder

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No, there are many other options but the effective ones cost $$$$. I wrote a guide about all of the effective treatments, you can see it here- viewtopic.php?f=11&t=63313

hmm, aside from RU, which seems tough to get right now, which one is significantly better than finasteride? which effective ones were you referring to?

money isn't a concern for me right now, i just want to hault and maybe even regrow 'some' of my front hairline with minimal sides.
 

CCS

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Most likely they will not publish the results, same as all the other phase II trials we read about.
 

img23

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I think by the end of these trials we should have a better understanding of what works and what doesn't. The person right before this post mentioned something about results not being published, not sure if they were referring to the 10 trials or another topic in this thread. I would expect the results would be made available, if not there is no reason to follow it any further.

Truth is, I think people need to accurately know if finasteride is really worth the time and money. Essentially if it is really that effective. A wonder drug it ain't, we know those early promises of big results didn't exactly pan out. I remember when it hit the scene in the late '90's, a lot of hopes and claims then, of course the reality is the positive results seem to be far more subtle. Again, how effective the med really is and what the true side effect profile is, that is what should be known completely.

Right now there are still a lot of things people are not 100% on with this drug. It may be the best thing out there right now, but that doesn't mean people shouldn't learn more about what they are taking.
 
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