Recent content by nate30

1. DHT drops -5ar2 is responsible for the conversion of testosterone to DHT. Finasteride is a 5ar2 inhibitor. 2. T increases by 20-40% -Because there is less testosterone being converted to DHT, the test level rises. I think it's more like 15-20% 3. Dopamine increases and serotonin decreases...

It's not easy to taper off in any meaningful fashion as .25mg has almost the same DHT inhibition (60%) as the full 1mg (70%). You'd need to get below the .1mg range would could be difficult to manage with just a pill splitter. Also I believe the drug's half life is 6 hours, so you'd have...

I don't believe the 5ar2 enzyme itself is directly responsible for hair loss, but one of its metabolites, DHT, is. It is the serum DHT level (95% reduction for Duta vs 70% for Fina) that is relevant. I agree that Duta doesn't have a reputation for causing substantially more regrowth than...

Ya itchy nipples isn't a super rare side effect. Could go away, could be the beginning of gynecomastia (due to increased Estrogenic activity). If you continue on it's pretty unlikely you'll develop full-on breasts, assuming you're at a healthy weight, but you could develop slightly...

Regarding superior regrowth with Dutasteride, Duta lowers DHT by 95%, and inhibits multiple types of 5ar. Finasteride lowers DHT by 70% and PRIMARILY inhibits 5ar2. Less DHT = more Estrogen dominance.

The body tries to preserve the normal T/E ratio so a rise in testosterone also means a rise in Estrogen. Finasteride users typically experience a 15% rise in Total T due to 5ar not converting it to DHT, but some men experience a drop in Free T in the long term, which is the more important...

Yikes. This isn't going to help Japan's problems with declining birth rates. http://www.techinsider.io/herbivore-men-in-japan-are-not-having-sex-8-15 -"Among male respondents, 17.9 percent reported little or no interest in having sex — or even an extreme dislike of it," The Japan Times reports...

Proven, no, but finasteride does inhibit Allopregnanolone, which is thought to possibly play a role in mediating depression and anxiety. https://www.researchgate.net/public...of_Allopregnanolone_in_Depression_and_Anxiety

It's unlikely that such a thing as a "useless" hormone exists in nature. If DHT was no longer needed after puberty the body would have likely evolved to stop producing it after puberty. DHT is only part of the equation though, as 5ar serves more purpose that just converting T to DHT. Just...

The potential issue is that 5ar is also responsible for converting progesterone to allopregnanolone. Allopreg is thought to potentially play a role in mediating depression and anxiety: https://www.researchgate.net/publication/258443301_The_role_of_Allopregnanolone_in_Depression_and_Anxiety

+1 for obviously British humor. Talk about projecting...

I see a lot of guys on here saying that if you don't have problems after several months on the drug, you're home free. That is patently false. I took the drug for a few years before the sides caught up with me to the point that I had to quit. Part of the reason finasteride is so insidious for some men...

The whole birth control vs Finasteride thing has been discussed a few times on the forum. Think about the role a man *typically* takes during intercourse, and the role a woman typically takes. That should hopefully illuminate why sexual dysfunction tends to be a bigger problem for men than for...

Perhaps, but I more got a kick out of the "learn to communicate with moral standards" bit. Very well put, but it's so at odds with the excessive hyperbole people like to employ on the Internet. I'm halfway tempted to make it a signature, haha. "Learn to communicate with moral standards, you...

Ha! Well said Saurab, yet for some reason the phrasing of your post has a highly humoristic flavor to me :)