Recent content by Maddy17

finasteride has a very short half life, like six hours. So it will be out of your system 2 days max. (Unlike dutasteride which can linger for weeks). I do not think you need to taper. Just stop taking it. But listen, it is crazy to take finasteride or spironolactone without knowing if you serum levels of androgen are...

Ok thinking further...5 AR enzyme also breaks down active cortisol to its inactive metabolite. So it could give you longer acting or higher levels of cortisol. Cortisol is a Gluco-cortoid. It stimulates glucose release from liver and in turn insulin...which drives weight and hunger (amongst...

The 5 alpha reductase enzyme that finasteride inhibits also reduces progesterone to allopregnenalone, a neuro transmitter. That is why it can cause anxiety and other mental issues. 5mg is a very high dose. What was your DHT level? What was your 3 adiol G level? If you are woman and DHT was...

I saw a top hair derm in NYC, Dr. Shapiro. He also has clinic in Canada. He is outside insurance and expensive. Like $800. But he was super nice and spent an hour. He prescribed finasteride, 2.5 mg once a day, and said 5% minoxidil NOT the foam because too much on hair not enough on scalp. He said...

hello again. Found today a new med which is beinn fast tracked by FDA, the pre-clinical name is VT-464, it inhibits 17/20 Lyase. Addresses adrenal testosterone and dhea. Trials done on prostate cancer and breast cancer (since it shuts down dhea and dhea is precursor for testosterone, andro...

Do you have elevated androgens? Or are they just throwing spironolactone at you for hair loss? Because thyroid hypo or hyper can cause hair loss. So if you just started therapy maybe see if that helps enough. My aunt is hypo. She told me once when they got the thyroid level right (which can be...

Oh, what isonomer are you talking about? I am a voracious reader and I want to know every biochemical and genetic thing I can. Anything you can point me too would be much appreciated. DHEA is exactly the issue on our androgen profile. How do I find out AR-genotype? Have done 23andme...

So you stopped shedding in a little over a month of every day dosage? did you shed more the first few weeks or anything?

Make sure they run T, both total and FREE T, andro, DHEA/DHEAS, DHT, SHBG, and 3-adiol (DHT metabolites) from an androgen perspective. Get the thyroid tests, as both hypo and hyper can cause hair loss, but if weight gain is problem hypo possible. T4, T3, free for both and reverse T3 and TSH...

So I can tell you are a man in the know by reading your posts. You asked above about DHT tests. Have you ever had 3-adiol tested. There is a longer technical name...which includes glucoranide or something at the end. In any case I have seen it abbreviated 3-adiol, and it is supposed to...

Estrogen causes upregulation of what? 5AR? I had heard that estrogen inhibits 5AR, actual estrodial but not ethinyl estrodial in BCP's. If you use progesterone, I think I read that you have to use ENOUGH. So low levels of progesterone can induce LH release, which will increase...

Hi, tried spironolactone. could not tolerate even 25mg. My blood pressure is low naturally like 105/60, heart rate can be as low as 54-57. It was awful. Because if it does lower your already low BP then what happens is as you get TOO LOW by your body's regulator decides, the brain calls for the...

Thank you Captain, maybe not as bad as I feared.

If I could get a prescription I would do it in a heartbeat. Have had no luck. I am in the US, NJ. One more appointment with a derm in three weeks, whom I had to pay $800 to see, half up front to hold appointment!

Ok, so I read a while back a study done in Egypt on women where they injected a mixture called Mesopecia into the scalp on an interval, 1x per week for 4 weeks, then 1x per every 2 weeks for a while, then monthly for like 2 months. The study was maybe 6-8 months. but there were before and...