Recent content by harold

Re: A recently discovered new factor in AA, the cure is near :) Hey all, Havent posted in a long time as i generally havent focussed much on hairloss and related issues in a few years. Was very interested to do a pubmed search to see if anything new had happened research wise and to see that...

Minoxidil increases the number of follicles that are formed in the Follica procedure according to one of the Cotsarelis patents. It being used isn't evidence of anything shady in and of itself.

This is important stuff because unlike a lot of studies that talk about hairloss in mice or genes involved in general hair loss or growth this was about a type of hairloss that is the same as male pattern baldness (progressive minituarization) AND it indicates that the central issue that creates this situation is...

Elevated aldosterone also found in balding women. Br J Dermatol. 2009 Nov 10. [Epub ahead of print] HYPERTENSION AND ALDOSTERONE LEVELS IN WOMEN WITH EARLY-ONSET ANDROGENETIC ALOPECIA. Arias-Santiago S, Guiérrez-Salmerón MT, Buendía-Eisman A, Girón-Prieto MS, Naranjo-Sintes R. San Cecilio...

The question is I guess does the elevation in aldosterone play a causative role in hair loss or is it perhaps another symptom of higher androgen levels. The authors of the above study do quote another study in which mice which were created to overexpress the mineralcorticoid receptor displayed...

This is a very interesting study for me. From the discussion: "This study found significantly higher systolic BP values and aldosterone levels in alopecic vs. nonalopecic individuals. Hirsso et al.1 reported a higher frequency of hypertension in Finnish male patients with Androgenetic Alopecia over 63 years old...

Evening all. Been a while since I dropped by. This study is quite interesting. Seems to affirm the role of wnt signalling in male pattern baldness and for the first time hints that the DHT/androgen receptorcomplex is actually binding to beta-catenin and altering/lowering beta-catenin levels as i understand from...

Exactly. As for a "genetic" cure.....dont hold your breath. What we should be focussed on is more effective and specific treatments. That is where research of this kind and microarrays showing gene expression differences can really help. Otherwise you have to wait around for them to get gene...

The link between opioids and testosterone/DHT is interesting. It seems that testosterone is lowered because opioids cause the increased conversion of tesosterone to DHT - particularly in the brain/CNS. This triggers the HPTA to lower tesosterone production in turn. In fact finasteride has been...

Yeah sorry MB I was trying to back up what you were saying in that (from memory at least) it seemed that other posters were dismissing the results based on the fact that they occurred in mice and seemed to assume it was a study trying to grow hair in mice. Guess I had been reading too many...

I think elevated estrogen or possibly more specifically an altered estrogen to androgen ratio is definitely implicated in gyno but I dont think it plays much of a role in the other sexual sides that people report. A lot have people including myself have mucked around with aromatase inhibitors...

Can you give some evidence to support this? Specifically this claim "protect the cell and keep it healthy and strong from inflamtion and oxidants, this lowers the amount of Androgen recepots needed." I have never seen any evidence that may substantiate any of these claims. If anything androgen...

If anyone read the study its not actually talking about hair growth at all its about the effect of black tea on serum testosterone possibly mediated by an inhibition of 5 alpha reductase inhibition. No need to invoke immune systems or what have you (whether or not they play any significant role...

Yes only nizoral. I suspect you could get similar results from the shampoo. Since the article was Japanese originally some finer details may have been lost in translation. Eg from memory it says the participants used the lotion once daily during or after regular shampoo IIRC. So it is not...

Well for me it comes down to 2 reasons. Firstly if curcumin does have such an effect after oral consumption then that is not something that I would want for the same reason that I am no longer taking finasteride or anything like that - I dont want any systemic antiandrogenic effects. If you are the sort...