Recent content by Armando Jose

  1. Armando Jose

    Fgf and Wnt signaling interaction in the mesenchymal niche regulates the murine hair cycle clock

    Wnts signal change during the normal hair cycle, our scalp hair is asynchronous (one hair in anagen and other in telogen), then what happen when we used a med affecting all hairs? It is extrem complicated, ----, similar to your regime, but a lot of luck with your experimentation. Take care.
  2. Armando Jose

    Fgf and Wnt signaling interaction in the mesenchymal niche regulates the murine hair cycle clock

    It is only basic hair research, it is good but it is irrelevant for us. Is it the real cause for common baldness? We always need ask us, why this "X" factor only affects at certains hairs over the scalp?
  3. Armando Jose

    Alpha-ketoglutarate For Adipose Tissue Rejuvenation

    Sebum is deposited onto the skin surface via the sebaceous duct and when associated with a hair follicle, the outwardly moving hair shaft serves as a wick that facilitates sebum dispersion Also this paper...
  4. Armando Jose

    Early Closure Of The Cranial Sutures - The Cause Of Male Pattern Baldness

    What about this skull, from the Paracas ancient people in Peru, skull can be deformed, and curiously he conserved his hair, nearly 2000 years.....
  5. Armando Jose

    Alpha-ketoglutarate For Adipose Tissue Rejuvenation

    Clearly common baldness is not a recent issue and seem that we know moreless the same about it in centuries.
  6. Armando Jose

    Alpha-ketoglutarate For Adipose Tissue Rejuvenation

    Very interesting point and it is in the line of my idea where hardened sebum inside pilosebaceous unit is a key in this "movement". Hair shaft acts as a wick to move/eliminate sebum produced in the SG, larger hairs are more effcient in this task, then people (usually women) with long hair are...
  7. Armando Jose

    Starting To Wonder If Dht Is Really Relevant In male pattern baldness.....

    IMO, there is not such difference among sexes in the same race. Have you any references?
  8. Armando Jose

    Starting To Wonder If Dht Is Really Relevant In male pattern baldness.....

    OK, stress is related to scalp hairs, but stress affect al ALL hairs, it is not patterned issue. beards tes but scalp hair can be the same in both sexes, it is only cultural issue.
  9. Armando Jose

    Starting To Wonder If Dht Is Really Relevant In male pattern baldness.....

    Important level of androgens in scalp hairs are made inside them, and there s not significant differences among sexes It is a key
  10. Armando Jose

    An Interesting Study About Dht And Hair Growth In Mice

    In my theory DHT it is necesary to make an operative pilosebaceous unit in order to grow hair, but the excess can be detrimental. Th paper goes in this direction.
  11. Armando Jose

    Why Do We Have Hairs On Heads At The First Place?

    Very interesting question Mandar ...., The hairs seem insignificant but our body uses a lot of effort to create them, we just need to know that they were created at the same time as the brain, heart, etc. or even early. There are some articles on this topic. It is interesting to note that the...
  12. Armando Jose

    The Role Of Big And Wide Galea In Male Pattern Baldness.

    https://earthsky.org/human-world/year-in-space-human-body-twins-study Sadly both have the same scalp hair,....,
  13. Armando Jose

    The Role Of Big And Wide Galea In Male Pattern Baldness.

    Please read this paper https://pubmed.ncbi.nlm.nih.gov/30703252/ Hypoxia improves hair inductivity of dermal papilla cells
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