Recent content by AnteUp

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    Androgenetic Alopecia Pathway Update and Possible Cure

    I do not recommend using Azelaic Acid anymore. I will explain why. It has just come to my attention that Azelaic Acid does 2 things that will hinder and harm hair growth. First it decreases mitochondrial ATP synthesis. This is terrible for those of us that are trying to regrow hair. However...
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    Androgenetic Alopecia Pathway Update and Possible Cure

    I glanced over the Garza et al paper and I found out something interesting. Androgenetic Alopecia scalp has all the stem cells needed, but it is lacking only two progenitor cells: CD34 (aka CD34+) and CD200 (aka CD200hiTGA6hi). In an update to the thread I stated how wounding effects the hair follicle. When...
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    Androgenetic Alopecia Pathway Update and Possible Cure

    That was a mistake I made. Tretinoin helps treat cancer, so since our hair is being treated like a cancer, tretinoin which prevents cancer should help. It was a general comment I was trying to make so people would understand why it should work for hair growth. - - - Updated - - - The pros...
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    Atraric Acid a Potent Antiandrogen

    Atraric acid is sold by fragrance companies under three different names: Veramoss, Verymoss, and Evernyl. Simply do a search, find a seller, and buy it. Buy it as a powder or in solution in a liquid. Information about its solubility is online as well. Remember this is an experiment. Use it...
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    Androgenetic Alopecia Pathway Update and Possible Cure

    Oxidants cause oxidative stress. Now that is clear, I want to explain why oxidants can regrow hair. There are two primary reasons why oxidants can regrow hair: 1) Oxidants can decrease proteasome degradation. Therefore, it can act a Proteasome inhibitor. Remember that people in the...
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    Atraric Acid a Potent Antiandrogen

    I have known about Atraric Acid for many years. I learned about it because it is found in Pygeum bark, which many men use for BPH. I read about Ataric Acid a while back and no one seems to be that interested in it. This could be due to the fact that it comes from a natural source. However...
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    Androgenetic Alopecia Pathway Update and Possible Cure

    It does have a synergistic effect. You are decreasing the conversion of androgens to DHT and using Minoxidil for its regrowth properties. Minoxidil grown hair can be affected by androgens if those androgens are not blocked. - - - Updated - - - Atraric Acid a Potent Topical...
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    Androgenetic Alopecia Pathway Update and Possible Cure

    An update to my op Critical Read: http://ac.els-cdn.com/S0092867411007562/1-s2.0-S0092867411007562-main.pdf?_tid=a6837042-6596-11e4-8af9-00000aab0f01&acdnat=1415266024_afbb1972942da163e9f8076dab7fe2c2 CD34 stem cells: I found out that they are correlated with lef1 and TCF7. Activating tcf7...
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    Androgenetic Alopecia Pathway Update and Possible Cure

    Here is an update to the androgenetic alopecia pathway and information on important topics for hair growth. I will include information about products and a possible cure. 1)))Androgen receptors are the main key. The factors that act on them, such as DHT and other androgens kick starts the...
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    Why Azelaic Acid should work in theory

    DHT causes an increase in p53 and p21 expression, which leads to DKK1 apoptosis of the hair follicle. Azelaic acid represses p53 and p21. http://www.ncbi.nlm.nih.gov/pubmed/22859066 http://www.ncbi.nlm.nih.gov/pubmed/23278893 Also, apparently Azelaic acid competes with the NADPH sites...
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    OTHER enzymes in the pilosebaceous unit & skin that cause hair loss

    These “Other” enzymes are the key to hair loss and hair generation. Take a look at these figures, look closely. http://www.nature.com/srep/2013/130325/srep01528/full/srep01528.html#f1 http://www.frontiersin.org/files/Articles/21348/fphar-03-00034-HTML/image_m/fphar-03-00034-g001.jpg...
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    OTHER enzymes in the pilosebaceous unit & skin that cause hair loss

    Aside from 5 alpha reductase I, II, III which produces DHT, there are other enzymes that are involved in androgen driven hair loss. The ones I am talking about are 17 beta HSD, 3 alpha HSD, and 3 beta HSD. These are also found in male genitalia and the adrenals. Inhibiting steroidgenesis is...
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    Indole 3 Acetic Acid as a CRTH2/GPR44 Antagonist

    Indole 3 Acetic Acid is a plant auxin(hormone) and its derivatives are potent CRTH2 antagonists. I am wondering why it isn't discussed as being a possible topical to block Prostaglandin D2. Here is what intrigued me about it: 1) Potent CRTH2 antagonist 2) Cheap and widely available 3) Study on...
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