Exploring The Hormonal Route. Hair=life.

[corn_scoops]

@Nghtly used on estradiol pills to recover from reflex hyper and that worked for him. I personally use 2 mg e pills and 100 mg spironolactone, but I take a few days break a month. As long as you take frequent breaks and don’t take obscene doses you shouldn’t fry your nuts, and you shouldn’t have significant shrinkage either if you make sure you get erections daily.
The minimum for just e2 I’d say is like 2mg maybe but you may or may not see results on that dose. I can, but I’m kind of a hyper-responder to estradiol

Right now I'm in a third world country. I've been here trying to get residency for another passport to reduce my taxes, but while I'm here obviously the perks are I can afford medicine. Very easy. That's why the dutasteride mesotherapy was pretty cheap. However, the off-brand labeled Latin American estrogen pills don't even seem to do anything for me cuz I was on them for like 2 weeks and that was one time. I had a sore boob for one day but other than that I haven't felt anything. Maybe I need to actually order some tranny stuff from the US or something or get brand name prescriptions

 

[Dhtchud69]

Right now I'm in a third world country. I've been here trying to get residency for another passport to reduce my taxes, but while I'm here obviously the perks are I can afford medicine. Very easy. That's why the dutasteride mesotherapy was pretty cheap. However, the off-brand labeled Latin American estrogen pills don't even seem to do anything for me cuz I was on them for like 2 weeks and that was one time. I had a sore boob for one day but other than that I haven't felt anything. Maybe I need to actually order some tranny stuff from the US or something or get brand name prescriptions

The higher your test the higher the dosage needed usually.
spironolactone makes them more effective and is a pretty light AA.

 

[corn_scoops]

The higher your test the higher the dosage needed usually.
spironolactone makes them more effective and is a pretty light AA.

I see. I heard spironolactone is crap. But idk maybe I'll do 25mg of cypro with 50mg bica and 2mg test and try and get some results and slowly taper off and see how much I can tolerate dosing down until I see results fade

 

[sanodatto]

Being quite social these days, I often hear from people how they feel about bald people. For example, I recently heard girls in a conversation come to the conclusion that bald guys are terrible. Can you imagine how painful it would be for me to hear this if I were bald myself?
By the way, people often underestimate how difficult it is to fight baldness. The girls say, “Why is he bald? Couldn’t he have used Finasteride?”

I believe you but in my anecdotal experience it's women under 30 who are assholes about it, older, mature women consider hair preference inconsequential compared to if you're confident, have your sh*t together and your own money

 

[corn_scoops]

The higher your test the higher the dosage needed usually.
spironolactone makes them more effective and is a pretty light AA.

Why would you consider spironolactone over bica or cypro? Also if I hyper reflex should I still be taking 5 ar inhibitors

 

[Hemingwayfan]

Bicalutamide works by binding to ARs, thus inhibiting the action of androgens which bind to ARs in hair follicle cells.

Mechanism of Increased AR Expression​

1. Compensatory Response to Blocked ARs:

• As bicalutamide binds to ARs, it prevents androgens from activating these receptors. However, the body can detect this reduced AR activity. In response, there may be a compensatory mechanism whereby the body tries to restore normal androgen activity by increasing the number of ARs. This upregulation is a form of homeostatic balance attempting to maintain normal physiological functions despite the presence of an AR antagonist.

2. Long-Term Adaptation to Bicalutamide:

• Prolonged use of bicalutamide may lead to adaptive changes at the cellular level in tissues sensitive to androgens, such as the scalp. These changes can include not only increased AR expression but potentially changes in the sensitivity or functionality of these receptors. Over several years, this adaptation could either counteract the balding process more effectively or, paradoxically, might lead to a scenario where the increased number of ARs could exacerbate hair loss if bicalutamide becomes less effective or if not all receptors are blocked.

 

[corn_scoops]

Yea in theory I've always worried that bica could raise testosterone (obviously it does) but it's supposed to block receptors. But I suppose one could take it and the blocking not be effective but you just raised testosterone. So maybe hopping on bica was a bad idea first. However I hear so many stories of bica working and cypro not and vice versa.

 

[Dhtchud69]

Why would you consider spironolactone over bica or cypro? Also if I hyper reflex should I still be taking 5 ar inhibitors

It’s healthier to use and often has better results with e2 than bica. Cypro would have the best results probably, but it also has the worst side effects from what I’ve read

 

[Almas_NW0]

After observing various people on this forum and reading their treatment stories, I have come to the conclusion that HRT remains the most effective treatment. In this thread there were bold statements like “Bicalutamide is as effective as HRT”, or “RU will 100% stop your hair loss.” But some statistics and my personal experience show that HRT alone increases your chances of stopping baldness by close to a hundred percent.

Bicalutamide did not help me, it seems to me that it gets worse on RU + Bicalutamide. And I’m even too lazy to try CPA because my life experience with hair loss is too pessimistic for me to believe in anything. I don’t have the moral strength to trust any treatment again. All I got was shattered expectations and disappointment. Only HRT showed me that this was possible.

 

[Mr. Slap Head]

Oral RU

 

[corn_scoops]

After observing various people on this forum and reading their treatment stories, I have come to the conclusion that HRT remains the most effective treatment. In this thread there were bold statements like “Bicalutamide is as effective as HRT”, or “RU will 100% stop your hair loss.” But some statistics and my personal experience show that HRT alone increases your chances of stopping baldness by close to a hundred percent.

Bicalutamide did not help me, it seems to me that it gets worse on RU + Bicalutamide. And I’m even too lazy to try CPA because my life experience with hair loss is too pessimistic for me to believe in anything. I don’t have the moral strength to trust any treatment again. All I got was shattered expectations and disappointment. Only HRT showed me that this was possible.

Yea people in here seem to be happy coming off finasteride and stuff and just using e2 injections. When I sift through all the unnecessary unproductive comments I actually find good advice but unfortunately I have to keep searching through this hell hole of a forum.

 

[4141241241241]

Yea people in here seem to be happy coming off finasteride and stuff and just using e2 injections. When I sift through all the unnecessary unproductive comments I actually find good advice but unfortunately I have to keep searching through this hell hole of a forum.

didn't like everyone still use finasteride/dutasteride even on hrt? also most of the useful info is on the first 300 pages so don't bother reading past that

 

[losingbattle88]

Guys I can't lie. I had slow mediate hairloss only in the temples and one day I used topical finasteride opposed to swallowing my dutasteride 0.5 pills and my hair randomly the next morning thickened up ( I had a thin spot and now I saw baby hairs com in) then out of nowhere I got muscle cramps and my whole body ached and I got diffuse thinning. I've been diffusely thinning every since even in my donor when I had thick full head of hair with slight temple recession. I'm pretty sure this is reflex hyper andronicty because I never even had acne till now. Will taking hrt solve this?

Receptor upregulation is real. Or hormonal imbalance dutasteride thinned my hair very fast for 1.5 years finasteride does the same but dutasteride worse. Litteraly after quitting dutasteride hair stopped thinning but took 3 months.

Yea people in here seem to be happy coming off finasteride and stuff and just using e2 injections. When I sift through all the unnecessary unproductive comments I actually find good advice but unfortunately I have to keep searching through this hell hole of a forum.

Going natural is the best side effect free regimen my friend.

 

[Almas_NW0]

Going natural is the best side effect free regimen my friend.

It's called «throw up one's cards».

 

[Mr. Slap Head]

It's called «surrended».

?

 

[Almas_NW0]

?

throw up one's cards. Give up.

 

[Mr. Slap Head]

throw up one's cards. Give up.

Gambit is a beast do you like X-men

 

[Almas_NW0]

Gambit is a beast do you like X-men

X men are those with two X chromosomes?

 

[losingbattle88]

throw up one's cards. Give up.

Im ok dont worry about me cutie pie.

 

[Mr. Slap Head]

X men are those with two X chromosomes?

It’s a comic superhero series. Good movies. No, it doesn’t have to do with chromosomes. There are male and female characters. You should check it out