@Mitko1 Balding and severely balding people statistically have lower testosterone. It is likely that the aponeurotic galea expresses DHT and thereby locally increases expression and activates androgen receptors at a specific site. Also men with enlarged prostate also have lower testosterone. This can be explained by the fact that epitestosterone, a powerful inhibitor of 5AR and a weak inhibitor of androgen receptors, is expressed together with testosterone in the proportion ~1:1. With age, when testosterone decreases, epitestosterone also decreases, and the proportion changes in favor of testosterone, which will cause more DHT in tissues, as if compensating for the lack of testosterone.
In the areas that are not balding, on the back of the head and on the sides, epitestosterone levels are higher. Because of what? Who knows. Maybe the muscles store it or express it, thus protecting the follicles next to them from DHT.
Although it would be more appropriate to ask why epitestosterone levels are lower in the balding area.
In the areas that are not balding, on the back of the head and on the sides, epitestosterone levels are higher. Because of what? Who knows. Maybe the muscles store it or express it, thus protecting the follicles next to them from DHT.
Although it would be more appropriate to ask why epitestosterone levels are lower in the balding area.