Pyridoxine Cyclic Phosphate 3%
Pyridoxine Cyclic Phosphate is a potent inhibitor of the 5-alpha-reductase enzyme. This is the enzyme most responsible for the "root cause" of hair loss in both men and women with Androgenetic Alopecia. Topical Antiandrogens like S5 Cream, and ingredients like this one, work to stop hair loss from further progression. 5-alpha-reductase (also known as 5ar) is what converts testosterone into dihydrotestosterone (DHT), and of course it is DHT which we all know must be stopped. With increased levels of DHT come increased levels of sebum and inflammation on the scalp, which all contribute to degradation of hair quality, thickness, and hair counts. Pyridoxine Cyclic Phosphate disrupts 5ar, which in turn disrupts the development of DHT, thus allowing hair to grow freely, and unhindered.
Pyridoxine Cyclic Phosphate is unique because it has superior thermostability and photostability compared to its counterpart vitamin B6 which you'll find in most hair and skin care products. An added benefit is its stability in hot conditions, which means it will continue doing its job even in hot weather and direct sunlight, unlike other forms of the same ingredient. More importantly - it has anti-inflammatory properties. And this is huge for prevention of hair loss. PCP is active against inflammatory markers IL-8 and IL-6 which often increase when the skin is damaged by UV rays. This makes this ingredient beneficial for reducing typical symptoms of androgenetic alopecia, and subsequently allowing for healthy hair growth.
Part of the Big Three
This product is one of the "Big Guns" for both men and women. There are several anti-androgens which are taken orally that could cure hair loss. The problem is, some of them will also wreak havoc on your hormone system. Antiandrogens are in the group known as the "Big Three" that many of our members use. This three-pronged approach prevents (antiandrogens), stimulates (growth stimulants), and calms (anti-inflammatories) for the best possible chance of results after 1 year of use. The typical Big Three is Propecia, Rogaine, and Nizoral (or Regenepure DR Shampoo). Spironolactone works for many women orally, but is not an option for men due to feminizing effects.
How Does it Work?
Follione DHT Scalp Therapy absorbs only into the scalp skin, and locally stops the formation of DHT, as well as blocks androgen receptors in the follicle. This product is a perfect complement to a Revivogen / Tricomin regimen as well, which provide a natural alternative to Propecia / Rogaine. The owner of this site has successfully used Topical Spironolactone as the core of his hair maintenance regimen for over 10 years. If you're looking to add re-growth to the equation, you will need to include a growth stimulant. If you just want to stop further loss, combining it with Revivogen or Propecia (or both) is the way to go.
Setting Your Expectations
Please remember that treating hair loss is a slow process that requires persistence and patience. Any legitimate hair loss treatment will take between 6-12 months to begin working, and a full 2 years before optimal results are attained. So set your expectations accordingly.
There may be shedding periods in between. Shedding is a natural part of any effective treatment regimen. Existing hairs are ejected and new, healthier hairs are generated in their place. It does not always happen, but it should be expected. Especially any time you modify your treatment regimen. This is why starting small (with 1-3 core products) and waiting 6 months to a year before adding anything new, is an important part of treating hair loss effectively.
Take photos of your hair in bright light, both wet and dry. This will help you keep perspective as time goes on. Especially through shedding periods which may cause you to think you've lost more hair. Photos will help you see that things haven't gotten any worse.
Follione DHT Scalp Therapy Ingredients:
Aqua, Dimethyl Isosorbide, Glycerin, Pyridoxine Cyclic Phosphate, Propanediol, Arginine, Lactic Acid, Glycine Soja Germ Extract, Triticum Vulgare Germ Extract, Scutellaria Baicalensis Root Extract, Copper Tripeptide-1, Fisetin, Raspberry Ketone, Ajuga Reptans Cell Culture Extract, Methylisothiazolinone, Acetyl Tetrapeptid-3, Melatonin
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