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Balding Dermal Papilla Secretions Delay Hair Growth

Androgens are required for scalp hair follicle miniaturisation in androgenetic alopecia, but their mechanism of action is unclear. The mesenchyme-derived dermal papilla is probably the key tissue in…

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Modifying Calcitonin Gene Related Peptide for Hair Growth

We studied the effect of SP and CGRP on human hair growth using organ culture model in which isolated hair follicles were grown in vitro. We devided the culture plates into four groups…

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Inhibiting Hair Growth with Endothelin Receptors

In this study, we examined the mechanism of hair regression induced by endothelins in in vivo and in vitro study. Histological examination revealed that the catagen-like morphological change of anagen…

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IGF-1 May Increase Miniaturization of Hair Follicles

In this investigation we have designed to find out whether Dermal Papilla cells secrete growth factors like IGF-1, and the effect of androgens on their expression of the above growth…

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Does Age Affect Hair Growing Protein Synthesis?

The objective of the study was to determine whether age affects the concentration of free amino acids in hair roots in men from the UK..

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The Human Hair Cycle and Epidermal Proteins

In order to investigate how the expression of epidermal proteins associated with differentiation also occurs in hair follicles according to its cycle, we performed immunohistochemistry and…

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Neurotrophins Affect Hair Cycles via Dermal Papilla Secretions

Neurotrophins have several non-neuronal functions in the skin. Previously we have shown that p75 kD neurotrophin receptor plays an important role during HF morphogenesis and that neurotrophins…

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The Hair Bulge as a Source of Keratinocyte Stem Cells

One of the most accepted means to identify keratinocyte stem cells takes advantage of the fact that they are normally rarely cycling in vivo, and can be detected experimentally as the…

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Correlation of Tooth Development and Hair Growth

Epithelial-mesenchymal interactions govern the initiation of organ development, subsequent morphogenesis and terminal cytodifferentiation. The developing tooth of the mouse is a good model for…

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Aromatase with Estrogen Role in Hair Growth

It is well known that sex hormones such as androgen and estrogen influence the hair growth in several animals. Aromatase is a member of cytochrome P-450 gene superfamily and…

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