Tissuse And J. Hewitt: Smart Hair Transplant Trial In 2019!

RolfLeeBuckler

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So Dr. Tsuji, lower your price or get fucked of Tissuse/ J. Hewitt :D

https://www.folliclethought.com/j-hewitt-to-trial-hair-multiplication-in-2019/

J. Hewitt to trial hair multiplication in 2019.

CEO Dr. Jon Knight: " We will start with 5 Japanese patients - maybe three men an two women or four men and just one woman but only Japanes subjects. We are planning by December of 2019 to start. If successful, SHT can be offered to patients around the world who would come to Japan, have hair biopsies, and then return in 45 days for injection of the Neo-papilla. So we will know this year I believe SHT is a viable treatment. It will not take years like REPLICEL/Shiseido or Tsuji, etc. it will be much sooner."
 

Throwaway94

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So Dr. Tsuji, lower your price or get fucked of Tissuse/ J. Hewitt :D

https://www.folliclethought.com/j-hewitt-to-trial-hair-multiplication-in-2019/

J. Hewitt to trial hair multiplication in 2019.

CEO Dr. Jon Knight: " We will start with 5 Japanese patients - maybe three men an two women or four men and just one woman but only Japanes subjects. We are planning by December of 2019 to start. If successful, SHT can be offered to patients around the world who would come to Japan, have hair biopsies, and then return in 45 days for injection of the Neo-papilla. So we will know this year I believe SHT is a viable treatment. It will not take years like REPLICEL/Shiseido or Tsuji, etc. it will be much sooner."

If they start in Dec 2019 how could they possibly know this year whether it's viable? Would take a good 6 months for the first glimpse of results and then god knows how much longer for a real phase 2 trial and commercialisation
 

MeDK

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Its always good with more competition.

But like we have seen with other treatments, that there might be a regrowth period and then back to baseline, we won't be able to know if we get something like that also, if they do a very short clinical trail, and then rush it to a phase 2 in japan (which can last 7 years before they need to reapply for approval).

So to me its good and yet something less good.

But of course its good if it keeps regrowth and not going back to baseline. Time will tell.
 

MeDK

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other treatments like what? and don't come with CB because that study makes absolutely no sense and some groups continued to gain anyway. and with rch-01 there was still a net gain after years and i suppose its not a one time treatment anyway

most if not all medical treatments loose their potency over time that you take regularly. The question is just how fast.

Most people might have experienced it with alcohol or painkillers or so, at some point the body compensates for the intake, and you have higher tolerances and therefore need to take more than before.

But too like I said its good with the competition for the rest of the field of hairloss regenerative medicine, that someone dares to make a short phase 1 trail (i assume) and then start on phase 2 conditional release in Japan. And what most of us have learned, some treatments take at least 6 months to show real results, and others more than a year, like hair transplants and such.

So if they believe they can show results in months with their treatments then its good, but how potent is it with regrowth, and does it last or do you have to do the treatment multiple times too maintain or so. Could be that is boost hair growth but you lose it again because it doesn't really solve the hair loss problem. and if that is so, then you have limited treatments because of limited number of healthy hair follicles on your head of course.

But all of this time will tell of course, and I do hope for good results from them
 

Joxy

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How much this scientific approach is similar to Tsuji, Stemson or Replicel?

For me the real cure will come with CRISPR/Cas9 technology, but that is still decade away at least.
 

MeDK

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actually those ell therapies are the only things that do solve the problem at its root unlike minoxidil and finasteride, that is the degeneration of the dermal papilla and its cell count and potency to induce hair growth

That is something we don't know for now. We hope it re-establishes the hair, but we don't know if there is a fall back, like when we already started to lose our hair. That is an interesting question that needs to be asked.

But lets see, replicel have their long term research and now this company with their short term research, let us see what happens, and really we only know when this have been on the market for some years or decades to know the real long term effects.
 

Joxy

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That is something we don't know for now. We hope it re-establishes the hair, but we don't know if there is a fall back, like when we already started to lose our hair. That is an interesting question that needs to be asked.

But lets see, replicel have their long term research and now this company with their short term research, let us see what happens, and really we only know when this have been on the market for some years or decades to know the real long term effects.
It is not short term research. Behind Tissuse are Roland Lauster and Gerd Lindner. Both university professors at Technische Universität Berlin. Their research is at least 12 years long.
 

MeDK

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It is not short term research. Behind Tissuse are Roland Lauster and Gerd Lindner. Both university professors at Technische Universität Berlin. Their research is at least 12 years long.

But how much of their research in this field have been done on humans?

Not many researchers can claims to do "everyday" research in humans with stem cell treatment for hair loss.
 

Joxy

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But how much of their research in this field have been done on humans?

Not many researchers can claims to do "everyday" research in humans with stem cell treatment for hair loss.
These guys are behind Tissuse


So, that was almost decade ago. I agree with you. Only clinical trial on humans will answer many questions. The best way to learn is through clinical trials.
 

Joxy

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Someone made an interesting comment about this procedure:

Shiseido doesn't use the same kind of cells as J. Hewit/TissUse is purportedly using. Shiseido uses Replicel's technology which involves non-inductive Dermal Sheath Cup cells while J. Hewitt/TissUse claims to use DP cells plus other cells and the cells are inductive. The difference between non-inductive cells and inductive cells is a big deal. The difference is so big that it could be the ballgame.

This legit info?
Can you explain us what is the difference between inductive and non-inductive cells?
 

MrV88

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So Dr. Tsuji, lower your price or get fucked of Tissuse/ J. Hewitt :D

https://www.folliclethought.com/j-hewitt-to-trial-hair-multiplication-in-2019/

J. Hewitt to trial hair multiplication in 2019.

CEO Dr. Jon Knight: " We will start with 5 Japanese patients - maybe three men an two women or four men and just one woman but only Japanes subjects. We are planning by December of 2019 to start. If successful, SHT can be offered to patients around the world who would come to Japan, have hair biopsies, and then return in 45 days for injection of the Neo-papilla. So we will know this year I believe SHT is a viable treatment. It will not take years like REPLICEL/Shiseido or Tsuji, etc. it will be much sooner."

LoL they don't answer, but we get Infos via follicle xD
 

Cymro27

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Holy fckin sh*t, out of nowhere BOOOM!

View attachment 127568


This looks like the exact same thing replicel is doing though, somebody know what the difference is?


It's closer to what Tsuji is doing
Someone made an interesting comment about this procedure:

Shiseido doesn't use the same kind of cells as J. Hewit/TissUse is purportedly using. Shiseido uses Replicel's technology which involves non-inductive Dermal Sheath Cup cells while J. Hewitt/TissUse claims to use DP cells plus other cells and the cells are inductive. The difference between non-inductive cells and inductive cells is a big deal. The difference is so big that it could be the ballgame.

This legit info?

Pretty much.. they are using the different types of cells you need to create a follicle and expanding them.
They then use a 3d scaffold which keeps the right cells in the right place so that they stay in the correct role (sorry if I'm teaching my father how to f**k - but it's the simplest way to explain it). They can actually grow mini hair shafts in vitro using this method.
I suppose the question is whether it can grow in to a full size hair in the human scalp once implanted.
They've done it successfully on mice which we all know what that means... nothing really.
 

ZP31

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How could this treatment “lose potency” if it’s a hair transplant with seemingly unlimited graphs?

Get this and take finasteride and you are set for life.
 

MeDK

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How could this treatment “lose potency” if it’s a hair transplant with seemingly unlimited graphs?

Get this and take finasteride and you are set for life.

If it doesn't lose potency, according to you, why would you then take finasteride?
 

ZP31

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If it doesn't lose potency, according to you, why would you then take finasteride?

Find me a good transplant surgeon that doesn’t prescribe finasteride for transplant patients. It’s a pretty well known thing.

But theoretically, these new follicles should be immune (or at least more resistant) to miniatureization, if the cells used are from the DHT resistant donor area.
 

MeDK

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Find me a good transplant surgeon that doesn’t prescribe finasteride for transplant patients. It’s a pretty well known thing.

But theoretically, these new follicles should be immune (or at least more resistant) to miniatureization, if the cells used are from the DHT resistant donor area.

you do know its not a hair transplant? they cultivate some cells and then inject it back into the scalp. So it should be beyond all of finasteride.

But human trails will tell how well and potent it really is. All we can do is speculate from now and until we have real data for from their trails.
 

OneDay_NW0

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Find me a good transplant surgeon that doesn’t prescribe finasteride for transplant patients. It’s a pretty well known thing.

But theoretically, these new follicles should be immune (or at least more resistant) to miniatureization, if the cells used are from the DHT resistant donor area.

Lol, it's not like they cloning a whole hair and putting this new hair into your scalp^^ Those new hairs won't need finasteride, thats one of the main ideas from this treatment.
 

Cymro27

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Find me a good transplant surgeon that doesn’t prescribe finasteride for transplant patients. It’s a pretty well known thing.

But theoretically, these new follicles should be immune (or at least more resistant) to miniatureization, if the cells used are from the DHT resistant donor area.

They take samples from the traditional donor area which is more resistant to dht, they are cloning cells taken from that area so the new hairs created in the lab should also be resistant.
finasteride is prescribed with a transplant to prevent further hair loss on the top.

Okay, so it's not like replicel that "restores" existing hair follicles.

This method creates new follicles? So it's more like a hair transplant procedure?

Pretty much, only the new follicles are pretty tiny.
 
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