Tissue regeneration experiments

[buzzmenot]

http://www.cbsnews.com/stories/2007/02/ ... HQO0.shtml

Think this topical will help out with e.g. tricomin and derma roller? They seem to work on similar principles... I wonder if a young child's ability to turn vellus hairs terminal (or regrow a finger tip) and an adult's differs not just because of fibrosis but stuff like this..

 

[hedgehog_info]

there have been many articles like the one above and below. The question all is about how to control the signals and only allow hair growth to occur. Very small changes in concentration of certain factors can have pronounced effects on HF stem cells. Such as turn on the hair cycle, repair damaged skin, or if not regulated tumorgenesis.

[Role of hair follicle stem cell in wound healing and correlative signals]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2007 Jan;21(1):90-3

Authors: Wang H, Chen B, Hu D

OBJECTIVE: To review the research progress of hair follicle stem cell (FSC) in wound healing and correlative signals. METHODS: The advances in the FSC location, characters, relations with wound repair and correlative singals were introduced based on the recent related literature. RESULTS: FSC played an important role in hair follicle cycle and wound healing. The correlative signals maybe Wnt, bone morphogenetic protein/transforming growth factor beta, Norch, Shh and fibroblast growth factor. CONCLUSION: The multipotency and plasticity of FSC offer a new way in regeneration medicine and the signals in cell proliferation and differentiation will be the new focus in future research.



PMID: 17305013 [PubMed - in process]