Systemic resorption of Ketoconazole in nanominox-MS ??

[Lannister]

Hello,

I am a NW3 with receding hairline in the temple region. I began using finasteride 9 Months ago trying filling up my receding hair loss. Began using conventional minoxidil (Regaine 5%) 6 Months ago. I noticed a stabilizing of my vertex region prior to using minoxidil (propably due to finasteride), however I didn`t notice any regrowth at all and even no significant shedding..........

So I would enjoy a little filling up (maybe to become a Norwood 2.5), so I discovered Nanominox by sinere.com, And i discovered their product Nanominox-MS, which is supposed to contain Minoxidil-Sulphate.
They state that one theory, why minoxidil does not work in everyone is due to low sulferase activity in the scalp, and I thought that this could be my case, soi thought about trying it out.....

Now to my question:
However their Product Nanominox-MS does contain Ketoconazole. So I am kind of worried that due to possible systemic resorption (Liposomes as a carrier vehicle) ketoconazole flushes into my system, and we all know that ketoconazole is a potent antiandrogen and was used in prostate cancer therapy for that purpose.

So does anyone know if this is possible ???

Has anyone any experience wth the nanominox-MS ???


Thanks in advance,
L.

 

[rusty_y2k2]

I seem to remember when I asked they said the ket was at a 0.5% concentration - so that's 1/4 the conc found in the prescription shampoo.

Not a direct answer to your question, I know but thought it might give you a frame of reference.

My answer is to email them about your concerns and ask about it - i've found them to be reply quickly and helpfully.

I've been using the FMS for approaching 1.5 months, haven't noticed any strength losses down the gym or other low androgen related problems. Let me know what they say if you do contact them about it though!

 

[Lannister]

Hey Rusty:

Here is the answer I got from sinere:

""-------------------------------------------------------------
"1) nanominox is full, no space for additional substances left. Also it
does not make sense to have two completely similar products with regard to
the ingredients.

2)We don`t plan to produce nanominox-MS without ketoconazole at the moment.

I understand your concern. But liposomal vehicles are very different. One
can design liposomes in order to facilitate transdermal delivery but one
can also design liposomes in order to increase retention in the skin.
PG-liposomes are suitable for drug delivery to the skin, read our page for
mre informations on PG-liposomes.
Nevertheless, so far there were no experiments done which investigated the
systemic absorption of ketoconazole from our product.

Greetings,
sinere-advisor
"---------------------------------------------------------------------------


Hope that helps,


Anyway, I am still looking for someone with expierence in these nanominox -MS or -FMS Products .....


anyone ????



L.