Study to Assess the Efficacy of PRP ( Platelet-Rich Plasma )

Armando Jose

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[h=1]Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia.[/h]
Dermatol Surg.
2016 Apr;42(4):491-7. doi: 10.1097/DSS.000

Alves R[SUP]1[/SUP], Grimalt R.

[h=3][/h]
[h=3]Abstract[/h][h=4]BACKGROUND:[/h]Platelet-rich plasma (PRP) was identified as having a beneficial effect in alopecia and has been postulated as a new therapy for androgenetic alopecia (Androgenetic Alopecia).
[h=4]OBJECTIVE:[/h]To assess the efficacy of PRP for the treatment of Androgenetic Alopecia.
[h=4]MATERIALS AND METHODS:[/h]This was a randomized, placebo-controlled, double-blind study in 25 patients with Androgenetic Alopecia. Platelet-rich plasma was injected in half-head and the other half-head with placebo. Each patient received a total of 3 treatments of PRP, 1 month apart.
[h=4]RESULTS:[/h]Six months after the first treatment with PRP, significant differences were seen in mean anagen hairs (67.6 ± 13.1), telogen hairs (32.4 ± 13.1), hair density (179.9 ± 62.7), and terminal hair density (165.8 ± 56.8) when compared with baseline (p < .05). Platelet-rich plasma was also found to increase hair density when comparing with the control side (p < .05). For the first time, the authors found a correlation between anagen hairs and patients >40 years and beginning of Androgenetic Alopecia ≥25 years old (p < .05) and hair density and male sex, age ≤40 years, positive family history of Androgenetic Alopecia and >10 years of duration of the disease (p < 0.05).
[h=4]CONCLUSION:[/h]Application of PRP showed a positive effect on Androgenetic Alopecia and could be regarded as an adjuvant therapy for Androgenetic Alopecia.

http://www.ncbi.nlm.nih.gov/pubmed/27035501
 

Afro_Vacancy

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25 patients is a perfectly adequate sample size if they are measuring a large effect.

The potential concern is whether this is a biased sample (no idea), and if six months is long enough.
 
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