I'm not debating the validity of any of this as by choosing to take oral finasteride on a daily basis for decades, its not something i'm subscribing to.
But for completeness to the topic in the OP, i'll add this.
I mean, lets be real, there is actually no evidence of this "finasteride sticks around much longer in tissue up to 30 days". where do you think finasteride resides normally? its not like its swimming around in serum
I take it the Dr.s claiming finasteride has a 30 day half life in the follicle, are just referencing something like the following and putting it into layman's terms.
''The mean plasma elimination half-life of finasteride is 6 hours (range, 3 to 16 hours); however, the turnover rate for the type II 5-alpha-reductase enzyme complex is slow, with a turnover half-life of approximately 30 days''
I'm also guessing this would tally in with the reasoning to choose a 60 day interval in the OP study, if indeed that is the interval they used.
when you stop taking finasteride after 5-6 days DHT is normal levels again
Again if you read a bunch of the studies over the last 25 years, they often quote varying figures from one another.
''A single dose of finasteride suppresses serum DHT levels for up to 4 days''
''Upon discontinuation of finasteride, DHT levels return to normal within 14 days.''
''After 24 weeks of treatment Mean percent DHT levels returned to within 20% of baseline with finasteride at week 4''
Most long term users have got to the point where they take alot of these studies with a pinch of salt.
The interest lies in actual real world results like
@md2002, which I have already mentioned and whether there are other long term users on here who have been able to maintain on an even less frequent dose than his 1mg a week.
(
@badnewsbearer for clarity this is an oral 5-ari thread discussing its use with extended periods between doses, unless you are experimenting with applying topical finasteride once weekly, bi-monthly or at even longer frequency's you are probably discussing its use in the wrong thread)