Response to Microneedling Treatment in Men with Androgenetic Alopecia Who Failed to R

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alscarmuzza

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*full text link below with pics

Response to microneedling treatment in men with androgenetic alopecia who failed to respond to conventional therapy

Introduction: The efficacy of conventional therapy viz. finasteride and minoxidil in androgenetic alopecia (Androgenetic Alopecia) that is based on both preventing hair loss and promoting new hair growth, varies between 30% and 60%. This has led to a large number of patients unsatisfied who demand for a better cosmetic coverage over the scalp. Microneedling has recently been reported to be promising, effective and a safe treatment modality in the treatment of Androgenetic Alopecia. This augments the response of conventional therapy. Materials and Methods: Four men with Androgenetic Alopecia were on finasteride and 5% minoxidil solution since 2 to 5 years. Though there was no worsening in their respective Androgenetic Alopecia stages with the therapy, they showed no new hair growth. They were subjected to microneedling procedure over a period of 6 months along with their ongoing therapy. Patients were assessed with the use of the standardized 7-point evaluation scale and patients' subjective hair growth assessment scale. The patients were followed up for 18 months post microneedling procedure to assess the sustainability of the response. Results: All patients showed a response of + 2 to + 3 on standardized 7-point evaluation scale. The response in the form of new hair growth started after 8-10 sessions. The patients' satisfaction was more than 75% in three patients and more 50% in one patient, on patients' subjective hair growth assessment scale. The obtained results were sustained post procedure during 18 months follow-up period. Conclusion : Treatment with microneedling showed an accelerated response with addition of microneedling procedure leading to significant scalp density. This is the first case series to report the boosting effect of microneedling with respect to new hair follicle stimulation in patients with androgenetic alopecia who were poor responders to conventional therapy.

Dhurat R, Mathapati S. Response to microneedling treatment in men with androgenetic alopecia who failed to respond to conventional therapy. Indian J Dermatol [serial online] 2015 [cited 2015 Jun 14];60:260-3.

Available from: http://www.e-ijd.org/text.asp?2015/60/3/260/156361
 

benjt

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Worst study design ever.

  • Small sample size: Only four (!) men
  • No placebo control
  • No hair count or hair weight assessment
  • Assessment photos have been taken with different light than pre-treatment photos
They could have made basically any conclusion with such a small sample size, no placebo control, and no objective assessment measurements.

Their conclusion is completely unfounded based on objective and repeatable criteria.

Why are all the papers released in Indian journals so sh1ttty? They really need some quality control.
 
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