Repigmentation And New Growth Of Hairs After Anti–interleukin-17 Therapy With Secukinumab

[Chromedome1990]

Nothing compared to having NO HAIR. With gray hair, you can still buzz and look nice.

This is true. Gray hair can easily be mitigated, whereas balding is a constant uphill battle.

 

[kiwipilu]

Nothing compared to having NO HAIR. With gray hair, you can still buzz and look nice.

you state the obvious ...most of us (if not all) baldies would choose full head of hairs with 100% grey hair (me first). And buzz cut or dye. But I just say having no grey hair and full head of hair is the dream . no wories anymore. imagine one treatment which treat both issues in just one topical daily. ; )

 

[Cue Bald]

lol i wouldn;t really give a f*** if i had gray hair and i am 32.
infact if i had a full head of gray hair i would be overjoyed.
after all you can just dye it, then you would have a thick full NW1 of dark hair, and all the female attention would be back (looking younger and more dynamic)

 

[westonci]

Not sure if this has any relavance

https://www.ncbi.nlm.nih.gov/pubmed/8409518

 

[bassa]

Cannabinoids decrease the th17 inflammatory autoimmune phenotype.

https://www.ncbi.nlm.nih.gov/pubmed/23892791

Abstract
Cannabinoids, the Cannabis constituents, are known to possess anti-inflammatory properties but the mechanisms involved are not understood. Here we show that the main psychoactive cannabinoid, Δ-9-tetrahydrocannabinol (THC), and the main nonpsychoactive cannabinoid, cannabidiol (CBD), markedly reduce the Th17 phenotype which is known to be increased in inflammatory autoimmune pathologies such as Multiple Sclerosis. We found that reactivation by MOG35-55 of MOG35-55-specific encephalitogenic T cells (cells that induce Experimental Autoimmune Encephalitis when injected to mice) in the presence of spleen derived antigen presenting cells led to a large increase in IL-17 production and secretion. In addition, we found that the cannabinoids CBD and THC dose-dependently (at 0.1-5 μM) suppressed the production and secretion of this cytokine. Moreover, the mRNA and protein of IL-6, a key factor in Th17 induction, were also decreased. Pretreatment with CBD also resulted in increased levels of the anti-inflammatory cytokine IL-10. Interestingly, CBD and THC did not affect the levels of TNFα and IFNγ. The downregulation of IL-17 secretion by these cannabinoids does not seem to involve the CB1, CB2, PPARγ, 5-HT1A or TRPV1 receptors. In conclusion, the results show a unique cannabinoid modulation of the autoimmune cytokine milieu combining suppression of the pathogenic IL-17 and IL-6 cytokines along with boosting the expression of the anti-inflammatory cytokine IL-10.




Other stuff that inhibits:

https://www.selfhacked.com/blog/th17/

 

[br1]

Cannabinoids decrease the th17 inflammatory autoimmune phenotype.

https://www.ncbi.nlm.nih.gov/pubmed/23892791

Abstract
Cannabinoids, the Cannabis constituents, are known to possess anti-inflammatory properties but the mechanisms involved are not understood. Here we show that the main psychoactive cannabinoid, Δ-9-tetrahydrocannabinol (THC), and the main nonpsychoactive cannabinoid, cannabidiol (CBD), markedly reduce the Th17 phenotype which is known to be increased in inflammatory autoimmune pathologies such as Multiple Sclerosis. We found that reactivation by MOG35-55 of MOG35-55-specific encephalitogenic T cells (cells that induce Experimental Autoimmune Encephalitis when injected to mice) in the presence of spleen derived antigen presenting cells led to a large increase in IL-17 production and secretion. In addition, we found that the cannabinoids CBD and THC dose-dependently (at 0.1-5 μM) suppressed the production and secretion of this cytokine. Moreover, the mRNA and protein of IL-6, a key factor in Th17 induction, were also decreased. Pretreatment with CBD also resulted in increased levels of the anti-inflammatory cytokine IL-10. Interestingly, CBD and THC did not affect the levels of TNFα and IFNγ. The downregulation of IL-17 secretion by these cannabinoids does not seem to involve the CB1, CB2, PPARγ, 5-HT1A or TRPV1 receptors. In conclusion, the results show a unique cannabinoid modulation of the autoimmune cytokine milieu combining suppression of the pathogenic IL-17 and IL-6 cytokines along with boosting the expression of the anti-inflammatory cytokine IL-10.




Other stuff that inhibits:

https://www.selfhacked.com/blog/th17/

Been doing cannabis for 20yrs.. still balding.

 

[sinusoid]

Been doing cannabis for 20yrs.. still balding.

Personally I was a very heavy user for a decade (all day, every day). When I quit smoking in late 2016 is when my hair loss and graying both seriously picked up speed. THC is also an anti-androgen. This is interesting.

 

[br1]

Personally I was a very heavy user for a decade (all day, every day). When I quit smoking in late 2016 is when my hair loss and graying both seriously picked up speed. THC is also an anti-androgen. This is interesting.

Could also just have been a coincidence for you.. When you stop, you are older, and your balding usually would speed up with age...

For me, it seems to mainly help with anxiety, depression, etc.. Which I attribute partially to finasteride.

 

[Murkey Thumb]

Personally I was a very heavy user for a decade (all day, every day). When I quit smoking in late 2016 is when my hair loss and graying both seriously picked up speed. THC is also an anti-androgen. This is interesting.

When you gave up is probably when you first noticed, lets face it!

 

[nohairnolife]

Graying sucks but there's dyeing. Imagine if you could just dump toppik on your head and it would be exactly like having a full head of hair.

 

[champpy]

Graying sucks but there's dyeing. Imagine if you could just dump toppik on your head and it would be exactly like having a full head of hair.

Haha well that would be called wearing a wig.
Personally i hate the idea of faking it. Its stressful and takes time and you have limits on what you can do.
Whether dyeing gray hair or using toppik, to me its not a solution to the problem, its just masking it.

 

[neymarjr10]

Has anyone ever heard of Greyverse from Lucaas Meyer Cosmetics??

 

[bassa]

Been doing cannabis for 20yrs.. still balding.

Yes, but I bet you used cannabis for the thc... And that's exactly want you don't want... You want the cbd... So the weed you smoke is with thc... And the medicinal one is with cbd

 

[nohairnolife]

Haha well that would be called wearing a wig.
Personally i hate the idea of faking it. Its stressful and takes time and you have limits on what you can do.
Whether dyeing gray hair or using toppik, to me its not a solution to the problem, its just masking it.

Well dye can't fly off your head like a wig and it's cheaper than a system. But yeah it would be best if all of this could be solved for real

 

[br1]

Yes, but I bet you used cannabis for the thc... And that's exactly want you don't want... You want the cbd... So the weed you smoke is with thc... And the medicinal one is with cbd

THC is also medicinal.

But anyways, I am always after the plant as a whole.

 

[BalderBaldyBald]

Has anyone ever heard of Greyverse from Lucaas Meyer Cosmetics??

Most likely a scam, this smells poopoo

 

[neymarjr10]

Most likely a scam, this smells poopoo

I dont think it's a scam. they have pictures and one publication

 

[Seuxin]

I'm using CBD in enteric coated caps since neraly 2 years for others health issue. Don't think it will regrowth your hairs

 

[BalderBaldyBald]

I dont think it's a scam. they have pictures and one publication

Well pics of gray hair can be easily shopped, and when you take a look at ingredients...fruit extract, polypeptide, bla bla bla...

 

[bassa]

THC is also medicinal.

But anyways, I am always after the plant as a whole.

Correct thc CAN also be medicinal used... But using the whole plant doesn't mean you get both thc and cbd... Because the plants gets cultivated for either cbd or thc.... So a thc plant hardly contains cbd and vice versa..