Making liposomal RU58841

[bcapop]

According to this site (http://elsomresearch.com/learning/techn ... osomes.htm), you can make liposomes by:

Large liposomes are easy to make. All that is required is shaking phospholipids in water. These liposomes have very limited functions and are usually made of commercial lecithin, commonly found in food products. Commercial lecithin’s main function is as an emulsifying agent, improving the ability of oil and water to remain mixed.

How about buying some high quality lecithin and mixing this with RU? It should help the stability issue.

 

[stax]

A very good idea, ive always wanted to do this.


A guy on hairsite did this a while ago with good results.

 

[bcapop]

Found it

From: http://www.hairsite8.com/m604ru20/_disc604/000000dc.htm

"I have used a liposomic vehicle to deliver the RU58841. After reading the literature there is no doubt that RU58841 can be put into a liposomic vehicle and is more effective at penetrating to the deeper levels of the skin. There is a study available that describes the process for having RU58841 put into a liposomal cream base. The study shows that a standard hydro-alcoholic vehicle does not result in as much RU58841 making it to the dermis (and therefore the hair root & papilla). Instead it remains localized in the uppermost levels of the skin (i.e. the stratum corneum) where it wouldn't help at all.

I use a liposome base because the literature supports it and because it lessens the need for me to use the full amount cited in the stumptailed macaque studies. Admittedly the studies done utilized a 5% hydro-alcoholic solution were promising and showed that this type of vehicle worked. I just happened to be convinced that more of the drug can be delivered to the dermis level of the skin with a liposome and by hydrating the scalp.

So the question is, how exactly do we make it?

 

[Jacob]

I posted some time ago about some contraptions to help make liposomal topicals...also at Hairsite I think. :shock:

 

[bcapop]

I posted some time ago about some contraptions to help make liposomal topicals...also at Hairsite I think. :shock:

Link!

 

[Jacob]

I can't find it at the moment..but try Googl'n for "liposome extruder". I recall some were just hand-held, non-electric devices.

There might be a better term for what you'd be looking for though...

 

[bcapop]

Found another thing. A company sells "Empty Liposomes", which can mix any ingredient in them (if they fit though). I have send them email .

 

[DoctorHouse]

Jacob I am glad you and Erik D. have become such great friends. :innocent:

 

[Jacob]

bcapop..that sounds familiar too. Might have a hard time obtaining them?

DoctorHouse..I've been friends with him before..I'm sure. That's all I'll say :woot:

 

[DoctorHouse]

Jacob, why don't you come up with a liposomal topical for regrowing the hairline thicker.

 

[Jacob]

I'm hoping Juveline will do that..but I didn't come up with it :shakehead:

Any suggestions though?

 

[squeegee]

http://www.jarpharma.com/performance.htm or http://www.phlojelultra.com

 

[bcapop]

http://www.jarpharma.com/performance.htm or http://www.phlojelultra.com

You can't order those if you're just a consumer

 

[chris55]

bcapop, did you ever hear back from the company you emailed about using empty liposomes?

 

[bcapop]

bcapop, did you ever hear back from the company you emailed about using empty liposomes?

Yes the same response as above

 

[squeegee]

yes you can order Phlogel if you are a consumer... This is the best trans dermal carrier that body builders are using right now...really effective.. Just bought a 100g for $20. Fast shipping... go fast in your skin..and dry out without any residues.

 

[bcapop]

yes you can order Phlogel if you are a consumer... This is the best trans dermal carrier that body builders are using right now...really effective.. Just bought a 100g for $20. Fast shipping... go fast in your skin..and dry out without any residues.

I don't understand the instructions

http://www.phlojel.us/dl/PJU%20Tutorial.pdf

 

[bcapop]

Found another one without all the preparations. Just put in the powder and mix it. It's called Finaderm. It looks good to dissolve the RU in it.

http://www.universalkits.com/16oz-finad ... -4920.html

 

[hairsucks]

What do bodybuilders use this stuff for? and would this be a good delivery system for the RU then ?

 

[stax]

bcapop, have you got this figured out yet?


Id love to try this. RU in a liposmal vehicle that stays in the hair follicles only, i think this would work. I really want to do this this time.


BTW the owner of that site that carried Finaderm is in some legal trouble due to some steroid bust issues.