Kintor has started Phase 3 trial in China for Pyrilutamide

5minutesbeforemiracle

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because you want a comparison: you want to know to what extent the remedy is helpful in relation to no treatment (placebo). Since we know that hair loss is a b**ch, we assume that the hair loss will progress, i.e. the result with placebo will be worse. here, however, it has increased significantly, which is unusual and of course also makes the end result worse or more unreasonable overall. The success of KX would have been clearer if the placebo group had not had an improvement. Also, it's questionable why they had any improvement: seasonal shedding, continued use of other treatments (have heard from a few at Tressless who were convinced they were in a placebo group and therefore switched to finasteride etc.) or whatever. it remains unclear, I would say.
Yep, I agree with what you wrote. On top of the confounding factors you mentioned, it also looks like quite a few participants in the placebo group actually dropped out of the trial; presumably they noticed their hairloss progressing. Those people dropping out would've raised the average score of the placebo group. But the person I was replying to was saying that Kintor's a "complete failure" because the placebo group improved lmfao.

Btw, you say people on tressless were in the Kintor trial? Wasn't it in China? Of the 19 placebo patients that finished the trial, some of those Chinese people are posting on reddit tressless in English? Sounds sketch to me.
 

JohnDoe5

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because you want a comparison: you want to know to what extent the remedy is helpful in relation to no treatment (placebo). Since we know that hair loss is a b**ch, we assume that the hair loss will progress, i.e. the result with placebo will be worse. here, however, it has increased significantly, which is unusual and of course also makes the end result worse or more unreasonable overall. The success of KX would have been clearer if the placebo group had not had an improvement. Also, it's questionable why they had any improvement: seasonal shedding, continued use of other treatments (have heard from a few at Tressless who were convinced they were in a placebo group and therefore switched to finasteride etc.) or whatever. it remains unclear, I would say.
I also don't see any point to worrying about the placebo group. What matters is the active therapy group.
 

RoryGall29

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No one knows yet. AR upregulation might be a real thing and Kintor didn't want to risk it with 12 months.
Risk what? If customers find out that it's efficacy goes heavily down after 6 months no one will buy it anymore, what's the point of releasing it in the first place?
 
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