I have just started using P4 on scalp and face. I am not sure about efficacy in general compared to E2 but P4 is supposed to block both T and DHT. Since I don't need it on my entire scalp anymore, I am using it on the hairline and temples for about two weeks now although some nights I might forget or be too tired. It's a lot of work being me.When I started on this stuff I noticed these sensations on my scalp randomly throughout the day. It's hard to describe but it's like:
-hairs parting as a new one is sprouting, mostly mid scalp and crown area
-a 4 legged bug walking pushing hairs aside, mostly mid scalp and crown area
-numbness in certain areas - mostly forelock. I remember bridge also described this one.
I work in a cubicle so you can imagine these wonderful sensations throughout the day to add some excitement and put a smile on your face. They can last 1-3 seconds. The longest one was a one time 7 secs, I thought a bean stock was growing out of my head.
When you start a drug it's efficacy is strongest at the beginning, that's when I was feeling the above the most. As time went on it was less as I assume efficacy wears off. And this is one case in point why cycling is important so your body doesn't adapt to current regime. Also increasing the dose and trying other things, then coming back to the old things.
Recently when I threw in P to finish off an old batch I had I was feeling the above again more frequently. So it gave me the idea that maybe P should get more credit then we give it. I believe someone here attested to P being effective for the stubborn temple area - we'll see, as in my next cycle I plan to take P more seriously, and cut back on some of the other stuff my body has already made it's gains from. Will throw in bica too, makes sense to use. And since bica and dutasteride might not go well together I figure maybe dutasteride only twice a week. I always make the plan in advance and put it out on a Excel spreadsheet - what, how much and when. This way you are tracking everything and how you are responding. I firmly believe for each person it's about finding the right mix in terms of your individual biochemistry. This will save money, over doing it, and your organs having to process this stuff.