Bayer Prolactin Receptor Antibody For Male And Female Pattern Hair Loss

pegasus2

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Hope Medicine Inc. ('HopeMed'), a clinical stage innovative biopharmaceutical company, has recently announced that U.S. Food and Drug Administration (FDA) has approved its Investigational New Drug (IND) application for phase II study to evaluate HMI-115, a first-in-class monoclonal antibody drug in treating androgen alopecia
 

pegasus2

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great news, we will finally be able to get an idea about this therapy
Other companies make promises, HMI makes clinical trials.
Are you actually planning on taking part in these trials? Do you have to pay or how exactly does it work?
Yes. You have to go to the specified location every two weeks to receive an injection. You don't pay anything. You can't be on any other treatments, and you will likely need to have severe hair loss. Typically you have to be off other treatments for 6 months prior to the trial
 
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coolio

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The trials will probably be studying crown areas rather than frontal/hairline. They normally do that because crown loss is more consistent (read: easier to study). Hairlines & temples can vary wildly from one man to the next, both the rate of loss and the ease of reversal.
 

Janko

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Other companies make promises, HMI makes clinical trials.

Yes. You have to go to the specified location every two weeks to receive an injection. You don't pay anything. You can't be on any other treatments, and you will likely need to have severe hair loss. Typically you have to be off other treatments for 6 months prior to the trial
Me the day they open the center for the trial somewhere.
 

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Chads don't bald

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Other companies make promises, HMI makes clinical trials.

Yes. You have to go to the specified location every two weeks to receive an injection. You don't pay anything. You can't be on any other treatments, and you will likely need to have severe hair loss. Typically you have to be off other treatments for 6 months prior to the trial
Oh dang I wont really wanna get off finasteride tbh

Even though I believe this is a potential cure I don’t wanna risk it. Guess I’m paying full price lol

Plus my hair loss isn’t severe anyways
 

werefckd

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Pre-clinical experiment results showed that MHI-115 almost doubled the hair density of hairless macaques, and no significant shedding occurred even 4 years after stopping medication.
Almost doubling hair density is really nothing for an area that is already bald. If you go from 4 hairs/cm2 to 8 hairs/cm2 in an area that you used to have 100+ hairs/cm2 it doesn’t mean anything. So I hope that info is not accurate (and according to the pictorial results of those macaques I think the density virtually got much better)
 

pegasus2

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Almost doubling hair density is really nothing for an area that is already bald. If you go from 4 hairs/cm2 to 8 hairs/cm2 in an area that you used to have 100+ hairs/cm2 it doesn’t mean anything. So I hope that info is not accurate (and according to the pictorial results of those macaques I think the density virtually got much better)
I think this is explained by the fact that they called very short and thin hairs terminal hairs, hairs that we would typically call intermediate. All of those hairs grew to full thickness, and the vellus hairs too. The number of fully terminal hairs appears to have increased by a thousand fold
 

trialAcc

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Almost doubling hair density is really nothing for an area that is already bald. If you go from 4 hairs/cm2 to 8 hairs/cm2 in an area that you used to have 100+ hairs/cm2 it doesn’t mean anything. So I hope that info is not accurate (and according to the pictorial results of those macaques I think the density virtually got much better)
Pretty sure the areas classified as "bald" on the macaques still grew terminals in the triple digits, they just have more vellus then humans to start with so it's tough to predict what will happen I guess.
 
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