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Dutasteride Results are In!
Article by HairlossTalk.com
Glaxo releases 6 mo Dutasteride Results & announces submission of NDA to the FDA. We have the results on how well Dutasteride helped Hair Loss...
Dutasteride outperforms Propecia for hair loss in clinical trial results released
this month.
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Well
folks, your patience is starting to pay off. A new
treatment which has been in the sights of many hair loss
sufferers for many months has officially proven itself more
effective than Propecia at maintaining and regrowing
hair. The Chart to the left compares Dutasteride's
hair count results (Orange Bars) to 5 times the normal
Propecia dosage, and the hair counts it returns (Green
Bar). As you can see, though the difference may seem
only marginal, Dutasteride has proven itself superior, as a
0.1mg dosage can equal 5 times the Propecia dosage in effect
on hair count. |
Propecia used to hold the title as being the most effective
clinically proven hair loss treatment on the market. With an
83% maintenance rate after 2 years, it has helped millions of men
keep their hair. However, its relatively low success rate at
hair regrowth has been a major point against it. Only 5% of
users in the Propecia FDA trials saw moderate regrowth in the
Crown, and only 4% in the Vertex. Part of its lackluster
sales performance was due to the incredible patience its users
required. Sometimes taking up to 1 year to even see a
stoppage of hair loss, and nearly a year and a half for some to
see any thickening at all, many people just don't bother.
Patience is not a very common human trait. Those that stick
with it for a full year or more almost always are pleased with the
results, but those impatient types may have a new toy to play with
come the end of 2001.
Earlier
last month, Glaxo announced that it had submitted an NDA (New Drug
Application) to the FDA for GI198745, also known as Dutasteride,
for use with Benign Prostatic Hyperplasia. This is the same
original use for Finasteride, the active ingredient in
Proscar. It wasn't until men started experiencing hair
growth as a side effect, did they bottle it in 1mg form and call
it Propecia. So goes the story for Dutasteride.
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Dutasteride's
Method of Action
Dutasteride differs from
Propecia in that it blocks both types of the enzyme
5-Alpha Reductase, whereas Propecia blocks only one.
It is this enzyme that combines with Testosterone to
create DHT, which ultimately destroys hair. There
has been a longstanding debate as to whether blocking the
other type of enzyme will have any effect on hair
loss. Now we know. |
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Six Months
on Dutasteride |
As compared to six
months on Propecia...
 
- To discuss Dutasteride with others, view our: Dutasteride Forums.
- For more information on Propecia, view our Propecia Product Review
- Discuss Propecia with others: Propecia Forums
- Looking to buy Propecia online? Propecia Shop
HLT
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