Hair Loss Treatments
Hair Loss & Alopecia Information, Support, and Treatments
Page 1 of 3 123 LastLast
Results 1 to 10 of 23
  1. #1
    Senior Member casperz's Avatar
    Join Date
    Oct 2007
    Posts
    630

    Starting topical Asprin to supress prostaglandins

    I'm sure everyone has heard the news on prostaglandin D2:

    http://stm.sciencemag.org/content/4/126/126ra34

    Since aspirin works by inhibiting an enzyme that produces prostaglandins would topical aspirin have a chance of working to regrow hair?

    http://chronicle.uchicago.edu/950817/aspirin.shtml

    Regardless I think I'm going to start topical aspirin tonight. I'm thinking
    about a 5% solution mixed into minox.

    Tell me why it wont work.

  2. #2
    Senior Member Jacob's Avatar
    Join Date
    Apr 2005
    Posts
    3,499

    Re: Starting topical Asprin to supress prostaglandins

    I'm guessing the pills contain fillers that may not disolve well...haven't looked at an aspirin label lately though.

    Just some aspirin topical related links:

    http://www.thecompounder.com/alterna...spirin-topical

    http://aspirinandarnica.com/

    http://www.pkwy.k12.mo.us/pierre/doc...opicalprod.pdf

    http://www.livestrong.com/article/93...in-skin-cream/

  3. #3
    Senior Member casperz's Avatar
    Join Date
    Oct 2007
    Posts
    630

    Re: Starting topical Asprin to supress prostaglandins

    The study below is not related but talks about inflammation and COX signaling in mice which was inhibited by topical aspirin treatment and had an effect on fur.

    PDF: http://alturl.com/64o6v

  4. #4
    Senior Member casperz's Avatar
    Join Date
    Oct 2007
    Posts
    630

    Re: Starting topical Asprin to supress prostaglandins

    Wow... did not realize how many products contain aspirin or salicylic acid.

    I've got to believe someone has tried topical aspirin to combat hair loss but
    Google sure does not turn up any results showing it either working or not.

    It would be amazing if something like aspirin could work, maybe some of the long time posters here have heard of it being used before.

  5. #5
    Senior Member Jacob's Avatar
    Join Date
    Apr 2005
    Posts
    3,499

    Re: Starting topical Asprin to supress prostaglandins

    I remember it being discussed before..just not anyone using it for any length of time. "Aspirin" that is. Salicylic acid is in plenty of products..even some I've used.

  6. #6
    TravisB
    Guest

    Re: Starting topical Asprin to supress prostaglandins

    My guess is it won't work. It would be too simple if Aspirin which is on market for many, many years was an accidential treatment for baldness. First, I guess you would need a good vehicle, if it even has to work.

    But if you have time and desire, then experiment! Why not?

  7. #7
    Senior Member
    Join Date
    Mar 2005
    Posts
    2,150

    Re: Starting topical Asprin to supress prostaglandins

    Well someone trying to make this themselves did not take long. Here is the thing its still a work in progress I doubt its as simple as just inhibiting this. They mentioned this - prostaglandin PGD2 but also they said a derivative of this seemed to completely stop hair growth so you would need to inhibit both of those and who knows what other things could be found while they do this.
    I really doubt asprin is going to work the same way with the same effectiveness as an actual treatment formulated to target these.

  8. #8
    Senior Member
    Join Date
    Nov 2010
    Posts
    100

    Re: Starting topical Asprin to supress prostaglandins

    today I spent most of the day searching about this to find a way to inhibit prostaglandin D2 synthase enzyme

    1. aspirin >
    aspirin is a prostaglandin inhibitor but I'm not sure if it inhibits prostaglandin D2, as it's a special prostaglandin , and not much info are known about it
    people used aspirin for years and didn't note any effect on hair, maybe because people on aspirin don't experience any type of hair loss

    But I don't think that aspirin has any effect on AA

    2. Inorganic selenium compounds
    SeCl4, NaSeCo3, selenium disulfide
    I think that the first two have never tried for Androgenic Alopecia and they don't have any clinical usage in medicine , so I think that they will be tried in the next few years orally & topically. but they will have significant side effects if they are used orally because PG-D2 is an important factor on the brain

    selenium disulfide is already used topically on the scalp as a powerful antidandruff shamoo (head & shoulders clinical strength)
    selenium disulfide shampoos are used in two concentrations
    1% over the counter (head & shoulders clinical strength and other shampoos)
    2.5% available with prescribtion

    3. organic sources of selenium
    "egg" not the most sources but it's the best to be taken in a daily routin
    1 egg is sufficient for your daily requirement of selenium
    tuna fish is also very rich in selenium
    you can also find other sources of organic selenium in this link
    http://nutritiondata.self.com/foods-000 ... 00000.html

    4. mast cell stabilizers (e.g. chromoglicic acid)
    as PG-D2 is only synthesized away from the brain by mast cells "only"
    mast cell stabilizers are used in bronchial asthma as a nasal spray or an inhaler.


    I think if you want to try on yourself don't try aspirin but try chromoglicic acid solution/sprays + head & shoulders clinical strength + eat food rich in selenium

  9. #9
    Senior Member
    Join Date
    Nov 2008
    Posts
    260

    Re: Starting topical Asprin to supress prostaglandins

    I hope Merck isn't the only company researching PG-D2 blockers.

  10. #10
    Senior Member zeroes's Avatar
    Join Date
    Mar 2012
    Location
    Australia
    Posts
    662
    All internals.

    Morning:
    Aged Garlic Extract x 1

    Night:
    Turmeric x 1
    Resveratrol x 1
    Ginkgo Biloba x 1
    Aged Garlic Extract x 1
    Hair, skin and nails tab (Blackmores) x 1
    Silica x 1

    Re: Starting topical Asprin to supress prostaglandins

    I'm kind of confused, isn't aspirin suppose to 'thin' your blood? Isn't lack of blood to the head one of the reason's people loss their hair?

Similar Threads

  1. Masturbation, Sex & Prostaglandins
    By Viens in forum Alternative Treatments
    Replies: 9
    Last Post: April 29th, 2012, 11:23 PM
  2. Prostaglandins
    By otis in forum Alternative Treatments
    Replies: 0
    Last Post: January 9th, 2010, 02:50 PM
  3. Fat Facts & Prostaglandins
    By misterE in forum Men's General Hair Loss Discussions
    Replies: 0
    Last Post: June 7th, 2009, 04:38 PM
  4. Asprin topical and mask
    By blaze in forum Men's General Hair Loss Discussions
    Replies: 0
    Last Post: September 25th, 2005, 01:02 PM
  5. Using topical Asprin for an anti-inflammatory
    By blaze in forum Men's General Hair Loss Discussions
    Replies: 3
    Last Post: August 24th, 2005, 11:41 PM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •