New Odorless Topical Spiro Lotion

Article by HairlossTalk.com

HairlossTalk: So it actually binds to the receptor itself, rather than allowing DHT to do so, which as we know, is one of the root causes for hair loss in men?

Dr. Lee: Yes. It binds at the receptor site. The third thing Spironolactone can do, and this may be the most important, is that it actually converts some of the Testosterone into an estrogen. So it has a very good effect on stopping the processes occurring in the scalp which cause hair loss. In fact, before I made Xandrox, which is a combination of Minoxidil and Azelaic Acid, I was trying to make a combination of Minoxidil and Spironolactone. It didn't work. In the same base, the two eventually reacted with each other and created an awful smell, so it still has to be applied separately.

HairlossTalk: For someone using Minoxidil and Spiro, how would they avoid the smell?

Dr. Lee: Well they can be applied, essentially, one right after the other, fairly close together in time. It takes several hours for Spironolactone to react with Minoxidil, so by that time, it will already have been absorbed.

HairlossTalk: Spiro blocks the receptor site from DHT attaching, but what about Testosterone itself?

Dr. Lee: Spironolactone effectively blocks the receptor site so that neither DHT nor Testosterone can bind to it.



HairlossTalk: In your experience, how do Oral Finasteride (Propecia/Proscar) stack up to Topical Spiro as far as hair maintenance and regrowth?

Dr. Lee: There are several studies which show the effectiveness of each individually, but there are none which exist that compare the two for hair loss. For those who have any reservations about taking something systemically, or currently have side effects with Propecia, it's a good alternative. But it has its advantages and disadvantages. Advantages being that it does not have any side effects, it is effective, and it's quite inexpensive compared to Propecia. The downside is its less convenient to use... no more inconvenient than minoxidil, but it does have to be applied separately.

HairlossTalk: As we all know, there are many dangerous substances out there which could be applied topically and regrow hair or inhibit its falling out. The problem arises in that these substances absorb and can cause serious systemic side effects. It's been said that if scientists could find an effective topical that did not absorb and stay in its original form, it would be the Holy Grail of topical hair loss treatments.

Dr. Lee: (Laughs) .. It's not that Spironolactone doesn't absorb, its just that it gets metabolized, so it doesn't have any systemic effects.

- Read the Product Review for Men on Topical Spironolactone
- Read the Product Review for Women on Topical Spironolactone
- Men: Discuss Topical Spironolactone in our Men's Forums.
- Women: Discuss Topical Spironolactone in our Women's Forums.

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